Overview of the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) Project
Parminder S. Suchdev,Parminder S. Suchdev,Sorrel Namaste,Grant J Aaron,Daniel J Raiten,Kenneth H. Brown,Rafael Flores-Ayala +6 more
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TLDR
Key research questions and programmatic and research implications will inform global guidelines on the assessment of anemia and micronutrient status and will guide the development of a research agenda for future longitudinal studies are described.About:
This article is published in Advances in Nutrition.The article was published on 2016-03-01 and is currently open access. It has received 142 citations till now. The article focuses on the topics: Anemia & Population.read more
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Journal ArticleDOI
Biomarkers of Nutrition for Development (BOND)-Iron Review.
Sean Lynch,Christine M. Pfeiffer,Michael K. Georgieff,Gary M. Brittenham,Susan J. Fairweather-Tait,Richard F. Hurrell,Harry J. McArdle,Daniel J Raiten +7 more
TL;DR: A full appreciation of folate's history as a public health issue, its biology, and an overview of available biomarkers and their interpretation across a range of clinical and population-based uses are provided.
Journal ArticleDOI
Anemia epidemiology, pathophysiology, and etiology in low- and middle-income countries
TL;DR: In this paper, the authors outline definitions and classifications of anemia, describe the biological mechanisms through which anemia develops, and review the variety of conditions that contribute to anemia development.
Journal ArticleDOI
The Proportion of Anemia Associated with Iron Deficiency in Low, Medium, and High Human Development Index Countries: A Systematic Analysis of National Surveys.
Nicolai Petry,Ibironke Olofin,Richard F. Hurrell,Erick Boy,James P. Wirth,Mourad Moursi,Moira Donahue Angel,Fabian Rohner +7 more
TL;DR: The analyses suggest that the proportion of anemia associated with iron deficiency is lower than the previously assumed 50% in countries with low, medium, or high Human Development Index ranking, and should be based on an analysis of country-specific data.
Journal ArticleDOI
Adjusting ferritin concentrations for inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project
Sorrel Namaste,Fabian Rohner,Jin Huang,Nivedita L. Bhushan,Rafael Flores-Ayala,Roland Kupka,Zuguo Mei,Rahul Rawat,Anne M Williams,Daniel J Raiten,Christine A. Northrop-Clewes,Parminder S. Suchdev +11 more
TL;DR: This study contributes to the evidence base to guide decisions about how and when to adjust ferritin for inflammation and lends support for the use of internal regression correction to estimate the prevalence of depleted iron stores in regions with inflammation.
Journal ArticleDOI
Methodologic approach for the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project
TL;DR: The BRINDA project refines approaches to interpret iron and vitamin A biomarker values in settings of inflammation and malaria infection and suggests the use of a new regression approach as well as proposes an anemia framework to which real-world data can be applied.
References
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Child development: risk factors for adverse outcomes in developing countries
Susan P. Walker,Theodore D. Wachs,Julie Meeks Gardner,Betsy Lozoff,Gail A. Wasserman,Ernesto Pollitt,Julie A. Carter +6 more
TL;DR: The evidence is sufficient to warrant interventions for malaria, intrauterine growth restriction, maternal depression, exposure to violence, and exposure to heavy metals, including iron deficiency anaemia.
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What are biomarkers
Kyle Strimbu,Jorge A Tavel +1 more
TL;DR: Working definitions and a conceptual framework are provided to understand the roles of biomarkers in clinical research and considers select cases in which misunderstandings about the terms led to flawed research conclusions.
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A systematic analysis of global anemia burden from 1990 to 2010
Nicholas J Kassebaum,Nicholas J Kassebaum,Rashmi Jasrasaria,Mohsen Naghavi,Sarah Wulf,Nicole E. Johns,Rafael Lozano,Mathilda Regan,David J. Weatherall,David Chou,Thomas P. Eisele,Seth Flaxman,Rachel L. Pullan,Simon Brooker,Christopher J L Murray +14 more
TL;DR: Iron-deficiency anemia was the top cause globally, although 10 different conditions were among the top 3 in regional rankings, and Malaria, schistosomiasis, and chronic kidney disease-related anemia were the only conditions to increase in prevalence.
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Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995–2011: a systematic analysis of population-representative data
Gretchen A Stevens,Mariel M. Finucane,Luz Maria De-Regil,Christopher J. Paciorek,Seth Flaxman,Francesco Branca,Juan Pablo Peña-Rosas,Zulfiqar A Bhutta,Majid Ezzati +8 more
TL;DR: Children's and women's haemoglobin statuses improved in some regions where concentrations had been low in the 1990s, leading to a modest global increase in mean haemochemistry and a reduction in anaemia prevalence between 1995 and 2011.
Journal ArticleDOI
Anaemia in low-income and middle-income countries
TL;DR: Anaemia is disproportionately concentrated in low socioeconomic groups, and that maternal anaemia is strongly associated with child anaemia, and the epidemiology, clinical assessment, pathophysiology, and consequences of anaemia in low-income and middle-income countries are reviewed.