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P022 Galectin-3, galectin-9, and galectin-3 binding protein in patients with inflammatory bowel diseases

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This article is published in Journal of Crohn's and Colitis.The article was published on 2019-01-25 and is currently open access. It has received 3 citations till now. The article focuses on the topics: Galectin.

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Altered Bioavailability and Pharmacokinetics in Crohn’s Disease: Capturing Systems Parameters for PBPK to Assist with Predicting the Fate of Orally Administered Drugs

TL;DR: A meta-analysis of the systems parameters affecting oral drug pharmacokinetics was conducted in this paper , where the information gathered on intestine, liver and blood proteins and other physiological parameters was incorporated into a physiologically based pharmacokinetic (PBPK) platform to create a virtual population of Crohn's disease patients, with a view for guiding dose adjustment in the absence of clinical data in CD.
Journal ArticleDOI

Highlights on the Role of Galectin-3 in Colorectal Cancer and the Preventive/Therapeutic Potential of Food-Derived Inhibitors

TL;DR: A recent review as mentioned in this paper provides an updated summary of preclinical and observational human studies investigating the pathogenetic role of Galectin-3 in intestinal inflammation and colorectal cancer, as well as the potential of Gal-3 activity inhibition by plant-source food-derived bioactive compounds to control CRC onset/growth.
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