Book ChapterDOI
Passive Microfluidics — Ultra-Low-Cost Plastic Disposable Lab-on-a-Chips
Bernhard H. Weigl,Ron L. Bardell,Tom Schulte,Clint Williams +3 more
- pp 299-302
TLDR
A number of microfluidic devices have been developed that do not require any external power source or means for fluid movement, such as particle separators, valves, detection channels, mixers, and diluters.Abstract:
A number of microfluidic devices have been developed that do not require any external power source or means for fluid movement. They include particle separators, valves, detection channels, mixers, and diluters. Current applications for these devices include standalone blood plasma separators, and a variety of qualitative and semi-quantitative assays. Experimental data as well as the results of fluid modeling are shown.read more
Citations
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Journal ArticleDOI
Micro Total Analysis Systems. 1. Introduction, Theory, and Technology
TL;DR: In this article, the authors present a review of the book.http://www.reviewreviews.com/reviews/book-reviews-of-the-book
Journal ArticleDOI
Passively driven integrated microfluidic system for separation of motile sperm
TL;DR: A self-contained integrated microfluidic system that can separate motile sperm from small samples that are difficult to handle using conventional sperm-sorting techniques, and opens the way for convenient bioassays based on sperm motility including at-home motiles sperm tests.
Journal ArticleDOI
Xurography: rapid prototyping of microstructures using a cutting plotter
TL;DR: In this article, a cutting plotter with an addressable resolution of 10 /spl mu/m was used to cut microstructures in various films with thicknesses ranging from 25 to 1000 /spl µ/m.
Journal ArticleDOI
Microfabrication and test of a three-dimensional polymer hydro-focusing unit for flow cytometry applications
TL;DR: In this paper, a 3D hydro-focusing micro cell sorter for micro flow cytometry applications is described, which was microfabricated by means of SU-8 3D lithography.
Patent
Fluidic mixer in microfluidic system
TL;DR: In this article, the authors describe methods for mixing and separating multiphase fluids in three-dimensional microfluidic devices, where the inlet channels are disposed within different layers of a 3D device.
References
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Journal ArticleDOI
Quantitative Analysis of Molecular Interaction in a Microfluidic Channel: The T-Sensor
TL;DR: The T-sensor as mentioned in this paper is a recently developed microfluidic chemical measurement device that exploits the low Reynolds number flow conditions in microfabricated channels, allowing measurement of analyte concentrations on a continuous basis.
Journal ArticleDOI
Microfluidic diffusion-based separation and detection
Bernhard H. Weigl,Paul Yager +1 more
TL;DR: In this article, it is shown that small particles diffuse faster than larger ones, which allows separation of particles by size, and it is possible to design fluidic microchips in which separations, chemical reactions, and calibration-free analytical measurements can be performed directly in very small quantities of complex samples such as whole blood and contaminated environmental samples.
Journal ArticleDOI
Microchip systems for immunoassay: an integrated immunoreactor with electrophoretic separation for serum theophylline determination
Nghia Chiem,D. Jed Harrison +1 more
TL;DR: A glass microchip is described in which reagents and serum samples for competitive immunoassay of serum theophylline can be mixed, reacted, separated, and analyzed, creating a lab-on-a-chip.
Journal ArticleDOI
Miniaturization of analytical systems.
TL;DR: A range of new technologies, including micromachining and molecular self-assembly, are providing the means for further size reduction of analyzers to devices with micro- to nanometer dimensions and submicroliter volumes.
Book ChapterDOI
Applying Microfluidic Chemical Analytical Systems to Imperfect Samples
Paul Yager,Darrel J. Bell,James P. Brody,Dong Qin,Catherine R. Cabrera,Andrew Kamholz,Bernhard H. Weigl +6 more
TL;DR: In this paper, the authors present a series of devices for chemical separation and analysis based on the low Reynolds number properties of liquids flowing at slow speeds in small channels, allowing some types of function that are not possible in larger devices because of the possibility of bringing flows together.