Journal ArticleDOI
Pathogenic mechanisms of Trypanosoma evansi infections.
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TLDR
Several attempts have being made to unravel the clinical pathogenic mechanisms in T. evansi infections, yielding various reports which have implicated hemolysis associated to decrease in life span of erythrocytes and extensive erythrophagocytosis being among those that enjoy prominence.About:
This article is published in Research in Veterinary Science.The article was published on 2012-08-01. It has received 67 citations till now. The article focuses on the topics: Trypanosoma evansi & Surra.read more
Citations
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Case Report - A RARE CASE OF HUMAN TRYPANOSOMIASIS CAUSED BY TRYPANOSOMA EVANSI
RM Powar,V. R. Shegokar,Prashant P. Joshi,V. S. Dani,N. S. Tankhiwale,P. Truc,Jean Jannin,A. Bhargava +7 more
TL;DR: The patient was not immunocompromised and showed infestation with a parasite which normally does not affect human beings, so the use of suramin - the drug of choice in early stage African trypanosomiasis without any CNS involvement was advocated.
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Combatting African Animal Trypanosomiasis (AAT) in livestock: The potential role of trypanotolerance.
TL;DR: New insights into the genetic basis of trypanotolerance are described and the potential of exploring this phenomenon as an integral part of the solution for AAT is discussed, particularly, in the context of African animal production systems.
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Parasitological, serological and molecular survey of Trypanosoma evansi infection in dromedary camels from Cholistan Desert, Pakistan.
Sonia Tehseen,Nusrat Jahan,Muahammad Fiaz Qamar,Marc Desquesnes,Mirza Imran Shahzad,Stijn Deborggraeve,Philippe Büscher +6 more
TL;DR: This first study on the prevalence of surra in Cholistan Desert, Pakistan using a broad variety of diagnostic tests thereby emphasizing it as a risk for the dromedaries of Pakistan and supports using antibody detection tests, rather than parasitological and molecular examination, to assess surra prevalence in camels.
Journal ArticleDOI
African trypanosome control in the insect vector and mammalian host
TL;DR: Tsetse fly saliva and various trypanosome components including adenylate cyclases, DNA, a kinesin heavy chain, and variant surface glycoprotein (VSG) interfere with resistance and tolerance to infection.
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Trypanosoma vivax GM6 antigen: a candidate antigen for diagnosis of African animal trypanosomosis in cattle.
Davita Pillay,Julien Izotte,Regassa Fikru,Regassa Fikru,Regassa Fikru,Philippe Büscher,Hermogenes Mucache,Luis Neves,Alain Boulangé,Momar Talla Seck,Jérémy Bouyer,Jérémy Bouyer,Grant B. Napier,Cyrille Chevtzoff,Virginie Coustou,Théo Baltz +15 more
TL;DR: This study demonstrates that the TvGM6 is an excellent candidate antigen for the development of a point-of-treatment test for diagnosis of T. vivax, and to a lesser extent T. congolense, African animal trypanosomosis in cattle.
References
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Book
Clinical biochemistry of domestic animals
TL;DR: J.K. Kaneko, Serum Proteins and the Dysproteinemias, and M.H. Morris, The Vitamins.
Journal ArticleDOI
Lipid peroxidation: its mechanism, measurement, and significance.
Barry Halliwell,Susanna Chirico +1 more
TL;DR: An increased concentration of end products of lipid peroxidation is the evidence most frequently quoted for the involvement of free radicals in human disease, but it is likely that increased oxidative damage occurs in most, if not all, human diseases and plays a significant pathological role in only some of them.
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Lipid peroxidation and antioxidants as biomarkers of tissue damage.
TL;DR: The body has a hierarchy of defense strategies to deal with oxidative stress within different cellular compartments, and superimposed on these are gene-regulated defenses involving the heat-shock and oxidant stress proteins.
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Free radical metabolism in human erythrocytes.
TL;DR: Light is shed on the role of ROS both at physiological and pathological levels and the structural requirements of antioxidants for appreciable radical-scavenging activity and the mechanisms of free radical systems in erythrocytes are understood.
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