Journal ArticleDOI
Pattern of maternal f-cell production during pregnancy
TLDR
Comparison of the numbers of F-cells with the percentage haemoglobin F determined chemically indicated that the increase in maternal ha Hemoglobin F synthesis results from an increased production of F -cells rather than from anincreased synthesis of haenoglobin F by the F- cells.About:
This article is published in The Lancet.The article was published on 1977-08-20. It has received 58 citations till now. The article focuses on the topics: Pregnancy.read more
Citations
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Journal ArticleDOI
Severe Fetomaternal Hemorrhage: A Review
TL;DR: The inadequate outcome data indicate the need to follow infants born with large FMH into childhood to document the effect on the central nervous system and the role of intrauterine transfusion (IUT) needs to be better defined.
Journal ArticleDOI
Detection of fetal red cells in fetomaternal hemorrhage using a fetal hemoglobin monoclonal antibody by flow cytometry.
TL;DR: The laboratory determination of the level of fetal cells in maternal circulation remains an important support in the obstetrical management of women with suspected uterine trauma and in the proper dose administration of anti‐D for prevention of Rh hemolytic disease of the newborn.
Journal ArticleDOI
Fetal haemoglobin production and the sickle gene in the oases of eastern Saudi Arabia.
TL;DR: Findings indicate that the unusually elevated levels of Hb F are not due to an associated high frequency of a gene for hetero‐cellular herditary persistence of fetal haemoglobin in the oasis population, but rather from a genteically determind absolute increase in HB F production related in some way to the SS genotype.
Journal ArticleDOI
Fetal Hb production during acute erythroid expansion. I. Observations in patients with transient erythroblastopenia and post-phlebotomy.
TL;DR: Two patients who reached the highest F‐cell numbers were probably carriers of heterocellular hereditary persistence of Hb F, suggesting that this gene may play a role in determining the magnitude of F‐ cell production in anaemic patients.
Journal ArticleDOI
Applications of flow cytofluorometry to transfusion science.
George Garratty,P Arndt +1 more
TL;DR: Because flow cytometry analyzes single cells nondestructively, mixed cell populations can be identified, and with the use of a cell sorter, purified subpopulations, such as rare cells, can be recovered and analyzed.
References
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Journal ArticleDOI
Serum human chorionic gonadotropin levels throughout normal pregnancy.
Glenn D. Braunstein,Glenn D. Braunstein,Joan L. Rasor,Joan L. Rasor,Donald Adler,Donald Adler,Hal Danzer,Hal Danzer,Maclyn E. Wade,Maclyn E. Wade +9 more
TL;DR: No secondary rise in hCG levels was demonstrated, indicating that the nonspecific hCG immunoassays give spuriously high values for hCG during the last trimester of pregnancy.
Journal ArticleDOI
F-cells in the adult: normal values and levels in individuals with hereditary and acquired elevations of Hb F
TL;DR: A strong linear correlation between the amount of Hb F and proportion of F-cells was observed and this technique may prove useful in studies of a variety of disorders associated with HB F elevations and also in investigations of the mechanisms controlling the transition from fetal to adult hemoglobin during the course of human development.
Journal ArticleDOI
Fetal Hemoglobin Restriction to a Few Erythrocytes (F Cells) in Normal Human Adults
TL;DR: During adult life, the quantity of fetal hemoglobin (HbF) present in F cells--that is, rare erythrocytes which are reactive with rabbit antiserum to human HbF during microscopic immunodiffusion--is sufficient to account for all of the small quantity normally present in whole blood.
Journal ArticleDOI
Interaction of heterocellular hereditary persistence of foetal haemoglobin with beta thalassaemia and sickle cell anaemia.
TL;DR: Evidence is presented that the interaction of a gene for heterocellular HPFH with that for either β thalassaemia (βthal) or sickle cell haemoglobin (HbS) results in the production of significantly greater amounts of HbF than is usually found in β thalsenaemia or Sickle cell anaemia alone.