Pharmacological potential of ginseng and its major component ginsenosides
Zubair Ahmed Ratan,Mohammad Faisal Haidere,Yo Han Hong,Sang Hee Park,Jeong-Oog Lee,Jongsung Lee,Jae Youl Cho +6 more
TLDR
Ginseng could be a valuable resource for future drug development; however, further higher quality evidence is required as it may have drug interactions although the available evidence suggests it is a relatively safe product.About:
This article is published in Journal of Ginseng Research.The article was published on 2021-03-01 and is currently open access. It has received 185 citations till now. The article focuses on the topics: Ginseng.read more
Citations
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Bioactive Compounds in Anti-Diabetic Plants: From Herbal Medicine to Modern Drug Discovery
Ngan Tran,Bao Pham,Ly Le +2 more
TL;DR: Traditional medicine performed a good clinical practice and is showing a bright future in the therapy of diabetes mellitus, and some new bioactive drugs isolated from plants showed antidiabetic activity with more efficacy than oral hypoglycemic agents used in clinical therapy.
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Adaptogenic effects of Panax ginseng on modulation of immune functions.
Zubair Ahmed Ratan,Zubair Ahmed Ratan,Soo Hyun Youn,Yi Seong Kwak,Chang Kyun Han,Mohammad Faisal Haidere,Jin Kyeong Kim,Hyeyoung Min,You Jung Jung,Hassan Hosseinzadeh,Sun Hee Hyun,Jae Youl Cho +11 more
TL;DR: The role of ginseng as an immune-modulating agent is reviewed in attempt to provide a valuable starting point for future studies on the herb and the human immune system.
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Anticancer Activities of Ginsenosides, the Main Active Components of Ginseng.
TL;DR: Wang et al. as discussed by the authors reviewed and discussed all available literature in order to facilitate further research of ginsenosides in this manuscript and concluded that ginseng can work synergistically with already existing cancer therapies.
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Glycogen-based pH and redox sensitive nanoparticles with ginsenoside Rh2 for effective treatment of ulcerative colitis
TL;DR: In vitro tests showed that Rh2 NPs could effectively internalize and release Rh2 into RAW264, and protect cells from apoptosis (p), and exhibited typical pH and redox dual response release behaviour as well as the excellent in vivo safety.
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Ginsenoside CK induces apoptosis of human cervical cancer HeLa cells by regulating autophagy and endoplasmic reticulum stress
Qi Yin,Hua Chen,Run-Hui Ma,Run-Hui Ma,Yuan-Yuan Zhang,Miao-Miao Liu,Kiran Thakur,Kiran Thakur,Jian-Guo Zhang,Jian-Guo Zhang,Zhao-Jun Wei,Zhao-Jun Wei +11 more
TL;DR: Ginsenoside CK (GCK) has been studied for its anti-cancer activity in cervical cancer (CC) HeLa cells as discussed by the authors, which showed that GCK inhibited the proliferation of cervical cancer cells and caused alteration in cell morphology with an IC50 of 45.95 μM.
References
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Journal ArticleDOI
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Freddie Bray,Jacques Ferlay,Isabelle Soerjomataram,Rebecca L. Siegel,Lindsey A. Torre,Ahmedin Jemal +5 more
TL;DR: A status report on the global burden of cancer worldwide using the GLOBOCAN 2018 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer, with a focus on geographic variability across 20 world regions.
Journal ArticleDOI
Diagnosis and Classification of Diabetes Mellitus
TL;DR: The chronic hyperglycemia of diabetes is associated with long-term damage, dys-function, and failure of differentorgans, especially the eyes, kidneys, nerves, heart, and blood vessels.
Journal ArticleDOI
Obesity as a medical problem
TL;DR: The global epidemic of obesity results from a combination of genetic susceptibility, increased availability of high-energy foods and decreased requirement for physical activity in modern society, and should be regarded as an epidemic that threatens global well being.
Journal ArticleDOI
Free radicals, antioxidants and functional foods: Impact on human health
TL;DR: The present review provides a brief overview on oxidative stress mediated cellular damages and role of dietary antioxidants as functional foods in the management of human diseases.
Journal Article
Free Radicals, Antioxidants in Disease and Health
TL;DR: This mini-review deals with the taxonomy, the mechanisms of formation and catabolism of the free radicals, it examines their beneficial and deleterious effects on cellular activities, and it highlights the potential role of the antioxidants in preventing and repairing damages caused by oxidative stress.