Journal ArticleDOI
Phloroglucinol compounds of natural origin
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TLDR
This review covers the phytochemistry and pharmacology of naturally occurring phloroglucinols, describing 700 compounds and containing a total of 484 references.About:
This article is published in Natural Product Reports.The article was published on 2006-07-25. It has received 473 citations till now.read more
Citations
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Gold catalysis in total synthesis – recent achievements
TL;DR: The applications of gold catalysed reactions in total synthesis during the years since the last article are reviewed and literature analysis is conducted to evaluate the progress in this field.
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Phlorotannins as bioactive agents from brown algae
TL;DR: This review presents an overview of phlorotannins from marine brown algae with their health beneficial biological activities.
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In vitro antioxidant properties of crude extracts and compounds from brown algae
TL;DR: In vitro antioxidant chemical methods, used as a first approach to evaluate potential agents to protect from lipid oxidation in foods, confirmed that the brown algae crude extracts, fractions and pure components are comparatively similar or superior to synthetic antioxidants.
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Chemical components and its antioxidant properties in vitro: an edible marine brown alga, Ecklonia cava.
TL;DR: It could be suggested that phlorotaninns from this genus would be more potential candidates for the development of unique natural antioxidants for further industrial applications as functional foods, cosmetics and pharmaceuticals.
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Angiotensin-I-Converting Enzyme (ACE) Inhibitors from Marine Resources: Prospects in the Pharmaceutical Industry
Isuru Wijesekara,Se-Kwon Kim +1 more
TL;DR: The marine-derived ACE inhibitors and their future prospects as novel therapeutic drug candidates for treat hypertension are discussed.
References
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Hyperforin as a possible antidepressant component of hypericum extracts
TL;DR: It appears, therefore, that this non-nitrogenous constituent is a possible major active principle responsible for the observed clinical efficacies of the extract as an antidepressant and that it could also be a starting point for drug discovery projects engaged in the search of psychoactive drugs with novel mode of action.
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Bactericidal activity of phlorotannins from the brown alga Ecklonia kurome
TL;DR: The bactericidal effects of the phlorotannins were more pronounced than those of the catechins against food-borne pathogenic bacteria and were as effective against MRSA as against the other bacteria tested.
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Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum
TL;DR: DIF-1, the major bioactive species after purification, has now been identified using a combined microchemical, spectroscopic and synthetic approach and represents a new class of effector molecule.
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Inhibitory phlorotannins from the edible brown alga Ecklonia stolonifera on total reactive oxygen species (ROS) generation.
TL;DR: To discover sources of antioxidative activity in marine algae, extracts from 17 kinds of seaweed were screened for their inhibitory effect on total ROS generation in kidney homogenate using 2′,7′-dichlorofluorescein diacetate (DCFH-DA).
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Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase
TL;DR: It is concluded that hyperforin acts as a dual inhibitor of 5-LO and COX-1 in intact cells as well as on the catalytic activity of the crude enzymes, suggesting therapeutic potential in inflammatory and allergic diseases connected to eicosanoids.