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Open AccessJournal ArticleDOI

Photoacoustic imaging in cancer detection, diagnosis, and treatment guidance

TLDR
The role of photoacoustics and photoacoustic-augmented imaging techniques in comprehensive cancer detection, diagnosis and treatment guidance is examined.
About
This article is published in Trends in Biotechnology.The article was published on 2011-05-01 and is currently open access. It has received 548 citations till now. The article focuses on the topics: Molecular imaging.

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Biomedical photoacoustic imaging

TL;DR: The underlying physical principles of the technique, its practical implementation, and a range of clinical and preclinical applications are reviewed.
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A practical guide to photoacoustic tomography in the life sciences

TL;DR: The fundamentals of photoacoustic tomography are reviewed and practical guidelines for matching PAT systems with research needs are provided, and the most promising biomedical applications of PAT are summarized.
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Gold nanoparticles for photoacoustic imaging

TL;DR: An overview of the current state of research in utilizing gold nanomaterials for PA imaging of cancer, atherosclerotic plaques, brain function and image-guided therapy is provided.
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Photoacoustic Imaging: Contrast Agents and Their Biomedical Applications.

TL;DR: PA contrast agents are classified according to their components and function, and gold nanocrystals, gold‐nanocrystal assembly, transition‐metal chalcogenides/MXene‐based nanomaterials, carbon‐ based nanommaterials, other inorganic imaging agents, small organic molecules, semiconducting polymer nanoparticles, and nonlinear PA‐imaging contrastagents are discussed.
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Noninvasive Imaging of Nanomedicines and Nanotheranostics : Principles, Progress, and Prospects

TL;DR: Noninvasive imaging can be employed to visualize and quantify how efficient passive or active drug targeting is in individual patients and, on this basis, to preselect patients likely to respond to nanomedicine-based chemotherapeutic interventions.
References
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Cancer statistics, 2010

TL;DR: The American Cancer Society as mentioned in this paper estimated the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data regarding cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute, the Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries and mortality data from National Center for Health Statistics.
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Cytotoxicity of Nanoparticles

TL;DR: For nanoparticles to move into the clinical arena, it is important that nanotoxicology research uncovers and understands how these multiple factors influence the toxicity of nanoparticles so that their undesirable properties can be avoided.
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Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects.

TL;DR: Because malignant tumors no longer execute functions necessary for homeostasis (such as the production of adequate amounts of adenosine triphosphate), the physiology-based definitions of the term "hypoxia" are not necessarily valid for malignant tumor patients.
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Photoacoustic imaging in biomedicine

TL;DR: An overview of the rapidly expanding field of photoacoustic imaging for biomedical applications can be found in this article, where a number of imaging techniques, including depth profiling in layered media, scanning tomography with focused ultrasonic transducers, image forming with an acoustic lens, and computed tomography using unfocused transducers are introduced.
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Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging

TL;DR: Functional photoacoustic microscopy (fPAM) is reported, which provides multiwavelength imaging of optical absorption and permits high spatial resolution beyond this depth limit with a ratio of maximum imaging depth to depth resolution greater than 100.
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