Open AccessJournal Article
Photosensitized Oxygenation of a 7,8-Dihydro-8-Oxoguanosine Derivative - Formation of Dioxetane and Hydroperoxide Intermediates (Vol 117, Pg 474, 1995)
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This article is published in Journal of the American Chemical Society.The article was published on 1995-01-01 and is currently open access. It has received 74 citations till now. The article focuses on the topics: Dioxetane & Derivative (chemistry).read more
Citations
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Journal ArticleDOI
Oxidative damage to DNA: formation, measurement and biochemical features.
TL;DR: It was found that 8-oxoGua, which is generated by either hydration of the guanine radical cation or .OH addition at C8 of the imidazole ring, is a preferential target for further reactions with 1O(2) and one-electron oxidants, including the highly oxidizing oxyl-type guanin radical.
Book ChapterDOI
Oxidative damage to DNA: formation, measurement, and biological significance.
Journal ArticleDOI
Singlet Molecular Oxygen Reactions with Nucleic Acids, Lipids, and Proteins.
Paolo Di Mascio,Glaucia Regina Martinez,Sayuri Miyamoto,Graziella E. Ronsein,Marisa Helena Gennari de Medeiros,Jean Cadet +5 more
TL;DR: Emphasis is placed in this Review on the description of the main oxidation reactions initiated by 1O2 and the resulting modifications within key cellular targets, including guanine for nucleic acids, unsaturated lipids, and targeted amino acids.
Journal ArticleDOI
Characterization of spiroiminodihydantoin as a product of one-electron oxidation of 8-Oxo-7,8-dihydroguanosine.
TL;DR: In nucleosides at pH 7, 22 degrees C, the principal product is shown herein to be a spiroiminodihydantoin nucleoside, as a diastereomeric mixture, that can be characterized by NMR, ESI-MS/MS, and independent synthesis.
References
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Journal ArticleDOI
Oxidative damage to DNA: formation, measurement and biochemical features.
TL;DR: It was found that 8-oxoGua, which is generated by either hydration of the guanine radical cation or .OH addition at C8 of the imidazole ring, is a preferential target for further reactions with 1O(2) and one-electron oxidants, including the highly oxidizing oxyl-type guanin radical.
Book ChapterDOI
Oxidative damage to DNA: formation, measurement, and biological significance.
Journal ArticleDOI
Singlet Molecular Oxygen Reactions with Nucleic Acids, Lipids, and Proteins.
Paolo Di Mascio,Glaucia Regina Martinez,Sayuri Miyamoto,Graziella E. Ronsein,Marisa Helena Gennari de Medeiros,Jean Cadet +5 more
TL;DR: Emphasis is placed in this Review on the description of the main oxidation reactions initiated by 1O2 and the resulting modifications within key cellular targets, including guanine for nucleic acids, unsaturated lipids, and targeted amino acids.
Journal ArticleDOI
Characterization of spiroiminodihydantoin as a product of one-electron oxidation of 8-Oxo-7,8-dihydroguanosine.
TL;DR: In nucleosides at pH 7, 22 degrees C, the principal product is shown herein to be a spiroiminodihydantoin nucleoside, as a diastereomeric mixture, that can be characterized by NMR, ESI-MS/MS, and independent synthesis.
Related Papers (5)
Photosensitized Oxygenation of a 7,8-Dihydro-8-oxoguanosine Derivative. Formation of Dioxetane and Hydroperoxide Intermediates
Chimin Sheu,Christopher S. Foote +1 more