Journal ArticleDOI
Physico-mechanical properties of degradable polymers used in medical applications: A comparative study
Israel Engelberg,Joachim Kohn +1 more
TLDR
The physico-mechanical properties of degradable polymers used for medical applications have been characterized and flexural storage modulus as a function of temperature was determined by dynamic mechanical analysis.About:
This article is published in Biomaterials.The article was published on 1991-04-01. It has received 736 citations till now. The article focuses on the topics: Dynamic mechanical analysis & Differential scanning calorimetry.read more
Citations
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Journal ArticleDOI
The return of a forgotten polymer—Polycaprolactone in the 21st century
TL;DR: Polycaprolactone (PCL) was used in the biomaterials field and a number of drug-delivery devices for up to 3-4 years.
Journal ArticleDOI
Silk-based biomaterials
Gregory H. Altman,Frank Diaz,Caroline M. Jakuba,Tara Calabro,Rebecca L. Horan,Jingsong Chen,Helen H. Lu,John C. Richmond,David L. Kaplan +8 more
TL;DR: Studies with well-defined silkworm silk fibers and films suggest that the core silk fibroin fibers exhibit comparable biocompatibility in vitro and in vivo with other commonly used biomaterials such as polylactic acid and collagen.
Journal ArticleDOI
Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
Journal ArticleDOI
Silk as a biomaterial
Charu Vepari,David L. Kaplan +1 more
TL;DR: Silks are fibrous proteins with remarkable mechanical properties produced in fiber form by silkworms and spiders that are biocompatible when studied in vitro and in vivo.
Journal ArticleDOI
Mechanisms of polymer degradation and erosion
TL;DR: The most important features of the degradation and erosion of degradable polymers in vitro are discussed in this article, where a brief survey on approaches to polymer degradation and degradation is given.
References
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Journal ArticleDOI
Biodegradable polymers for use in surgery—polyglycolic/poly(actic acid) homo- and copolymers: 1
D.K. Gilding,A.M. Reed +1 more
TL;DR: In this paper, the historical development of polyglycolic acid (PGA) and polylactic acid (PLA) polymers and copolymers for use in surgery is set down.
Journal ArticleDOI
Crystallization and morphology of a bacterial thermoplastic: poly-3-hydroxybutyrate
TL;DR: In this paper, a number of interesting results on the physical properties of poly-3-hydroxybutyrate (PHB) were presented on crystallization kinetics, morphology of melt-and solution-crystallized PHB, the variation of lamellar thickness with crystallization temperature, and the assessment of some thermodynamic quantities.
Book ChapterDOI
The Role and Regulation of Energy Reserve Polymers in Micro-organisms
Edwin A. Dawes,P. J. Senior +1 more
TL;DR: The chapter considers the evidence for the energy-storage roles of glycogen, polyphosphates and poly-p-hydroxybutyrate, and the current state of knowledge concerning the regulation of their biosynthesis and degradation in the microbial cell.
Journal ArticleDOI
Aliphatic Polyesters II. The Degradation of Poly(DL-lactide), Poly(e-caprolactone), and Their Copolymers in Vivo
TL;DR: The mechanisms of biodegradation of poly (DL-lactide), poly (epsilon-caprolactone), and copolymers of epsilon-caproate sequences with DL-dilactide, delta-valerolactone, and DL-epsil on-decalactone in rabbit were shown to be qualitatively similar.
Journal ArticleDOI
Degradation rates of oral resorbable implants (polylactates and polyglycolates): Rate modification with changes in PLA/PGA copolymer ratios
TL;DR: Control of degradation rate of the implant could best be attained by varying the composition of PLA and PGA between 75% and 100% PLA along with a corresponding 25% to 0% PGA.