Journal ArticleDOI
Post-exposure prophylaxis after sexual exposure (PEPSE) awareness in an HIV-positive cohort.
TLDR
Post-exposure prophylaxis after sexual exposure (PEPSE) awareness was audited in an HIV-positive cohort and MSM, younger patients, and those diagnosed after 2006 were significantly more likely to be PEPSE aware.Abstract:
Post-exposure prophylaxis after sexual exposure (PEPSE) awareness was audited in an HIV-positive cohort. A total of 403 out of 828 (48.7%) patients were PEPSE aware. Patients diagnosed post-2006 were more PEPSE aware; 57.2% vs. 44.2% (p = 0.0004). Men who have sex with men (MSM) were more PEPSE aware; 65.8% vs. 39.1% in heterosexuals (p 35 years (p 400 copies/mL), awareness was 64.1%. Overall, PEPSE awareness was unexpectedly low. MSM, younger patients, and those diagnosed after 2006 were significantly more likely to be PEPSE aware. More than one in three patients with detectable viraemia were PEPSE unaware.read more
Citations
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Journal ArticleDOI
Current perspectives in HIV post-exposure prophylaxis
Binta Sultan,P Benn,Laura Waters +2 more
TL;DR: The implications of recent data from interventional and observational studies demonstrating significant reductions in the risk of HIV transmission within a serodiscordant relationship if the HIV-positive partner is taking effective ART upon PEP guidelines are considered.
Journal ArticleDOI
Antiretrovirals for Primary HIV Prevention: the Current Status of Pre- and Post-exposure Prophylaxis
TL;DR: A timely summary of recent progress in bio-behavioral prevention is provided by contextualizing the most noteworthy recent findings regarding PEP and PrEP to inform the successful implementation of these promising prevention approaches.
Journal ArticleDOI
UK guideline for the use of HIV Post-Exposure Prophylaxis Following Sexual Exposure, 2015.
Fiona V Cresswell,Laura Waters,Eleanor Briggs,Julie Fox,Justin Harbottle,David Hawkins,Martin Murchie,Keith Radcliffe,Paul Rafferty,Alison Rodger,Martin Fisher +10 more
TL;DR: The updated British Association for Sexual Health and HIV guidelines for HIV post-exposure prophylaxis following sexual exposure (PEPSE) are presented and the place of PEPSE within the broader context of other HIV prevention strategies is considered.
Journal ArticleDOI
2016 United Kingdom national guideline on the sexual health care of men who have sex with men.
Dan Clutterbuck,David Asboe,Tristan Barber,Carol Emerson,Nigel Field,Stuart Gibson,Gwenda Hughes,Rachael M. Jones,Martin Murchie,Achyuta V Nori,Michael Rayment,Ann Sullivan +11 more
TL;DR: This guideline is intended for use in UK Genitourinary medicine clinics and sexual health services but is likely to be of relevance in all sexual health settings, where men who have sex with men (MSM) seek sexual health care or where addressing the sexual health needs of MSM may have public health benefits.
Journal ArticleDOI
Adherence to Post-Exposure Prophylaxis (PEP) and Incidence of HIV Seroconversion in a Major North American Cohort
Réjean Thomas,Chrissi Galanakis,Sylvie Vézina,Danièle Longpré,Michel Boissonnault,Emmanuelle Huchet,Louise Charest,Daniel Murphy,Benoit Trottier,N. Machouf +9 more
TL;DR: Patients were more likely to be adherent to TVD-based regimens, older and male patients were also more adherent to treatment, and PEP regimen was associated with treatment adherence.
References
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Journal ArticleDOI
Prevention of HIV-1 Infection with Early Antiretroviral Therapy
Myron S. Cohen,Ying Q. Chen,Marybeth McCauley,Theresa Gamble,Mina C. Hosseinipour,Nagalingeswaran Kumarasamy,James Hakim,Johnstone Kumwenda,Beatriz Grinsztejn,José Henrique Pilotto,Sheela Godbole,Sanjay Mehendale,Suwat Chariyalertsak,Breno Santos,Kenneth H. Mayer,Irving F. Hoffman,Susan H. Eshleman,Estelle Piwowar-Manning,Lei Wang,Joseph Makhema,Lisa A. Mills,Guy de Bruyn,Ian Sanne,Joseph J. Eron,Joel E. Gallant,Diane V. Havlir,Susan Swindells,Heather J. Ribaudo,Vanessa Elharrar,David N. Burns,Taha E. Taha,Karin Nielsen-Saines,David D. Celentano,Myron Essex,Thomas R. Fleming +34 more
TL;DR: In this article, Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples.
Journal ArticleDOI
Prevention of HIV-1 infection with early antiretroviral therapy
TL;DR: The exciting evidence generated by this paper – that antiretroviral treatment of HIV-1 infection definitively reduces the risk of onward transmission of the virus by 96% – was rightly dubbed Science magazine's ‘Breakthrough of the Year’ in 2011.
Journal ArticleDOI
UK guideline for the use of post-exposure prophylaxis for HIV following sexual exposure
Martin Fisher,P Benn,Barry Evans,Anton Pozniak,Mike Jones,Suzie MacLean,Oliver Davidson,Jack Summerside,David Hawkins,Hiv +9 more
TL;DR: The updated British Association for Sexual Health and HIV (BASHH) guidelines for post-exposure prophylaxis (PEPSE) to HIV are presented and consideration is given to the place of PEPSE within the broader context of HIV prevention strategies and sexual health.
Journal ArticleDOI
Lack of awareness of HIV post-exposure prophylaxis among HIV-infected and uninfected men attending an inner London clinic.
TL;DR: An audit of HIV-infected and -uninfected men attending two clinics at an inner London treatment centre demonstrated an alarming lack of awareness of post-exposure prophylaxis following sexual exposure (PEPSE).
Journal ArticleDOI
Awareness of non-occupational HIV postexposure prophylaxis among French people living with HIV: the need for better targeting.
TL;DR: Factors associated with lack of PEP awareness were a low educational level, unemployment, older age, and CD4 cell counts <200, which indicated that having casual partners was associated with better awareness.
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