Journal ArticleDOI
Post-induction Strategies in Metastatic Colorectal Cancer Patients Treated With First-Line Anti-EGFR-Based Treatment: A Systematic Review and Meta-Analysis.
Alessandro Parisi,Michele Ghidini,Riccardo Giampieri,Gianluca Tomasello,Andrea Luciani,Claudio Ferri,Rossana Berardi,Fausto Petrelli +7 more
TLDR
A systematic review and metanalysis of randomized clinical trials (RCTs) investigating the efficacy of post-induction strategies after the first-line treatment with anti-Epidermal Growth Factor Receptor (EGFR) in patients with metastatic colorectal cancer (mCRC) are available as mentioned in this paper .About:
This article is published in Clinical Colorectal Cancer.The article was published on 2022-01-01. It has received 3 citations till now. The article focuses on the topics: Medicine & Medicine.read more
Citations
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Journal ArticleDOI
Current concepts of anti-EGFR targeting in metastatic colorectal cancer
TL;DR: The authors reviewed established concepts of tackling the EGFR pathway in metastatic colorectal cancer and provided insight into the growing field of liquid biopsy guided personalized approaches of EGFR inhibition in mCRC.
Journal ArticleDOI
Conversion Strategy in Left-Sided RAS/BRAF Wild-Type Metastatic Colorectal Cancer Patients with Unresectable Liver-Limited Disease: A Multicenter Cohort Study
Stefano Granieri,Christian Cotsoglou,A. Bonomi,Lisa Salvatore,Roberto Filippi,Olga Nigro,Fabio Gelsomino,Ina Valeria Zurlo,Ilaria Depetris,Riccardo Giampieri,Rossana Berardi,C. Morelli,Michele De Tursi,Michela Roberto,Elson Gjoni,Alessandro Germini,Nicola de’Angelis,Riccardo Memeo,Antonio Facciorusso,Ornella Garrone,Daryl Ramai,Michele Ghidini,Alessandro Parisi +22 more
TL;DR: In this paper, the authors explored the efficacy of a conversion strategy in a selected population of 272 left-sided RAS/BRAF wild-type colorectal cancer patients with liver-limited metastatic disease.
Journal ArticleDOI
Efficacy of different maintenance strategies for RAS wild-type colorectal cancer: A network meta-analysis.
Fausto Petrelli,Sara Cherri,Michele Ghidini,Gianluca Tomasello,Antonio Ghidini,Alberto Zaniboni +5 more
TL;DR: In this article , the authors performed a network meta-analysis (NMA) to compare the relative efficacy of different maintenance treatments for advanced RAS wild-type colorectal cancer (CRC).
References
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Journal ArticleDOI
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
TL;DR: Moher et al. as mentioned in this paper introduce PRISMA, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses, which is used in this paper.
Journal Article
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
TL;DR: The QUOROM Statement (QUality Of Reporting Of Meta-analyses) as mentioned in this paper was developed to address the suboptimal reporting of systematic reviews and meta-analysis of randomized controlled trials.
Journal ArticleDOI
Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
Journal ArticleDOI
Bias in meta-analysis detected by a simple, graphical test
TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
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