Journal ArticleDOI
Prediction of serum-cholesterol responses of man to changes in fats in the diet
Ancel Keys,Ancel Keys,Joseph T. Anderson,Joseph T. Anderson,Francisco Grande,Francisco Grande +5 more
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This article is published in The Lancet.The article was published on 1957-11-16. It has received 655 citations till now. The article focuses on the topics: Blood serum & Cholesterol.read more
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Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials
TL;DR: The effects of dietary fats on total:HDL cholesterol may differ markedly from their effects on LDL, and the effects of fats on these risk markers should not in themselves be considered to reflect changes in risk but should be confirmed by prospective observational studies or clinical trials.
Journal ArticleDOI
Cholesterol-lowering effects of dietary fiber: a meta-analysis
TL;DR: A meta-analysis of 67 controlled trials was performed to quantify the cholesterol-lowering effect of major dietary fibers, finding that increasing soluble fiber can make only a small contribution to dietary therapy to lower cholesterol.
Journal ArticleDOI
Quantitative Effects of Dietary Fat on Serum Cholesterol in Man
TL;DR: It is shown that minimal levels of serum cholesterol were achieved with oils with an iodine number of about 100, and that more highly unsaturated oils were not more effective, which implies that monounsaturated acids are half as effective as the diene, linoleic acid, the primary polyunsaturated acid in vegetable oils.
Journal ArticleDOI
Effect of dietary fatty acids on serum lipids and lipoproteins. A meta-analysis of 27 trials.
R P Mensink,M B Katan +1 more
TL;DR: All fatty acids elevated HDL cholesterol when substituted for carbohydrates, but the effect diminished with increasing unsaturation of the fatty acids, and that for monounsaturates was not.
Journal ArticleDOI
Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake.
TL;DR: Analysis of evidence from a wide variety of cross-sectional and intervention studies confirms that fatty acid biomarkers can complement dietary assessment methodologies and have the potential to be used more quantitatively.
References
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Journal ArticleDOI
A simplified method for the estimation of total cholesterol in serum and demonstration of its specificity.
TL;DR: The simplified but precise method described in this paper involves treatment of the serum with alcoholic potassium hydroxide to liberate the cholesterol from the lipoprotein complexes and to saponify the cholesterol esters.
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Effect of dietary fatty acids on serum lipids and lipoproteins. A meta-analysis of 27 trials.
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