Pregnancy in women with pulmonary hypertension
TLDR
Pregnancy should still be regarded as contraindicated in women with pulmonary hypertension, and pregnancy and delivery should be managed by multidisciplinary services with experience in the management of both pulmonary hypertension and high-risk pregnancies.Abstract:
Women with pulmonary hypertension have a high risk of morbidity and mortality during pregnancy. The inability to increase cardiac output leads to heart failure while further risks are introduced with hypercoagulability and decrease in systemic vascular resistance. There is no proof that new advanced therapies for pulmonary hypertension decrease the risk, though some promising results have been reported. However, pregnancy should still be regarded as contraindicated in women with pulmonary hypertension. When pregnancy occurs and termination is declined, pregnancy and delivery should be managed by multidisciplinary services with experience in the management of both pulmonary hypertension and high-risk pregnancies.read more
Citations
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Journal ArticleDOI
Statement on pregnancy in pulmonary hypertension from the Pulmonary Vascular Research Institute
Anna R. Hemnes,David G. Kiely,Barbara A. Cockrill,Zeenat Safdar,Victoria J. Wilson,Manal Al Hazmi,Ioana R. Preston,Mandy MacLean,Tim Lahm +8 more
TL;DR: This guideline document sought to discuss the state of knowledge of pregnancy effects on pulmonary vascular disease and to define usual practice in avoidance of pregnancy and pregnancy management, and drafted 38 consensus-based recommendations on pregnancy avoidance and management.
Journal ArticleDOI
Analysis of the susceptibility to COVID-19 in pregnancy and recommendations on potential drug screening.
TL;DR: Pregnant women are susceptible to COVID-19, and special attention should be paid to the selection of drugs that are both effective for maternal diseases and friendly to the fetus, and drugs that show superior maternal and fetal safety are worthy of consideration.
Journal ArticleDOI
Épidémiologie de la mortalité maternelle en France, 2007–2009
TL;DR: Maternal mortality is rather stable in France and may reach more reduction as deaths due to atony decreased as suboptimal care did, but the haemorrhages are the leading cause but their ratio is 1.9 versus 2.5 previously; this decrease results from the postpartum haem orrhage by uterine atony going down.
Journal ArticleDOI
Pulmonary Hypertension and Pregnancy Outcomes: Insights From the National Inpatient Sample
TL;DR: In a contemporary data set of pregnant women in the United States, PH was associated with an increase in MACE during the hospitalization for delivery, with an exceptionally elevated risk among women with associated cardiomyopathy.
Journal ArticleDOI
Pregnancy and pulmonary hypertension.
TL;DR: A systematic review of the literature on the use of targeted treatments for pulmonary arterial hypertension during pregnancy indicates a considerable decrease of mortality since a previous review in 1998, and a further non-significant decrease since the latest review in 2009.
References
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Journal ArticleDOI
Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)
Nazzareno Galiè,Marius M. Hoeper,Marc Humbert,Adam Torbicki,Jean-Luc Vachiery,J.A. Barberà,Maurice Beghetti,Paul A. Corris,Sean Gaine,J S R Gibbs,Miguel Ángel Gómez-Sánchez,Guillaume Jondeau,Walter Klepetko,Christian Opitz,Andrew J. Peacock,LJ Rubin,Michael J. Zellweger,Gérald Simonneau +17 more
TL;DR: In this paper, a review of the published evidence for management and/or prevention of a given condition is carried out by experts in the field and a critical evaluation of diagnostic and therapeutic procedures is performed including assessment of the risk/benefit ratio.
Journal ArticleDOI
ESC Guidelines on the management of cardiovascular diseases during pregnancy: the Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC).
Vera Regitz-Zagrosek,Carina Blomström Lundqvist,Claudio Borghi,Renata Cifkova,Rafael Ferreira,Jean-Michel Foidart,J Simon R Gibbs,Christa Gohlke-Baerwolf,Bulent Gorenek,Bernard Iung,Mike Kirby,Angela H E M Maas,João Morais,Petros Nihoyannopoulos,Petronella G. Pieper,Patrizia Presbitero,Jolien W. Roos-Hesselink,Maria Schaufelberger,Ute Seeland,Lucia Torracca,Jeroen J. Bax,A Auricchio,Helmut Baumgartner,Claudio Ceconi,Veronica Dean,Christi Deaton,Robert Fagard,Christian Funck-Brentano,David Hasdai,Arno W. Hoes,Juhani Knuuti,Philippe Kolh,Theresa McDonagh,Cyril Moulin,Don Poldermans,Bogdan Alexandru Popescu,Zeljko Reiner,Udo Sechtem,Per Anton Sirnes,Adam Torbicki,Alec Vahanian,Stephan Windecker,Carlos Aguiar,Nawwar Al-Attar,Angeles Alonso Garcia,Anna Antoniou,I M Coman,Uri Elkayam,Miguel Ángel Gómez-Sánchez,Nina Gotcheva,Denise Hilfiker-Kleiner,Róbert Gábor Kiss,Anastasia Kitsiou,Karen T S Konings,Gregory Y.H. Lip,Athanasios J. Manolis,Alexandre Mebaaza,Iveta Mintale,Marie Claude Morice,Barbara J.M. Mulder,Agnes Pasquet,Susanna Price,Silvia G. Priori,Maria J Salvador,Avraham Shotan,Candice K. Silversides,Sven O Skouby,Jörg Ingolf Stein,Pilar Tornos,Niels Vejlstrup,Fiona Walker,Carole A. Warnes +71 more
TL;DR: Recommendations for the prevention and management of venous thrombo-embolism in pregnancy and puerperium and the associated risk groups according to risk factors: definition and preventive measures are presented.
Journal ArticleDOI
Guidelines for the diagnosis and treatment of pulmonary hypertension
Marius M. Hoeper,Marc Humbert,Adam Torbicki,Jean-Luc Vachiery,Joan Albert Barberà,Maurice Beghetti,Paul A. Corris,Sean Gaine,J. Simon R. Gibbs,Miguel Ángel Gómez-Sánchez,Guillaume Jondeau,Walter Klepetko,Andrew J. Peacock,Lewis J. Rubin,Michael J. Zellweger,Gérald Simonneau,Angelo Auricchio,Jeroen J. Bax,Claudio Ceconi,Veronica Dean,Gerasimos Filippatos,Christian Funck-Brentano,Richard J. Hobbs,Peter Kearney,Theresa McDonagh,Keith McGregor,Bogdan A. Popescu,Zeljko Reiner,Udo Sechtem,Michal Tendera,Panos E. Vardas,Petr Widimsky,Felicita Andreotti,Michael Aschermann,Riccardo Asteggiano,Ray Benza,Rolf M. F. Berger,Damien Bonnet,Marion Delcroix,Luke Howard,Anastasia Kitsiou,Irene Lang,Aldo P. Maggioni,Jens Erik Nielsen-Kudsk,Myung H. Park,Pasquale Perrone-Filardi,Maria Teresa Subirana Domenech,Anton Vonk-Noordegraaf,José Luis Zamorano +48 more
TL;DR: Guidelines and Expert Consensus Documents summarise and evaluate all currently available evidence on a particular issue with the aim to assist physicians in selecting the best management strategies for a typical patient, suffering from a given condition, taking into account the impact on outcome, as well as the risk/benefit ratio of particular diagnostic or therapeutic means.
ESC Guidelines on the management of cardiovascular diseases during pregnancy The Task Force on the Management of Cardiovascular Diseases
Carina Blomström Lundqvist,Rafael Ferreira,Jean-Michel Foidart,Joshua D. Simon,R. Gibbs,Angela H.E.M. Maas,Petronella G. Pieper,Jolien W. Roos-Hesselink,Maria Schaufelberger +8 more
TL;DR: In this paper, the authors presented a list of risk factors for venous thrombo-embolism in pregnancy and puerperium in women with heart disease, including the following risk factors: hypertension, congestive heart failure, hypertension, age (>75 years), diabetes, stroke, and atrial septal defect.
Journal ArticleDOI
Prospective Multicenter Study of Pregnancy Outcomes in Women With Heart Disease
TL;DR: Pregnancy in women with heart disease is associated with significant cardiac and neonatal complications, despite state-of-the-art prenatal care, and the cardiac event rate can be predicted using a risk index incorporating these predictors.
Related Papers (5)
ESC Guidelines on the management of cardiovascular diseases during pregnancy: the Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC).
Vera Regitz-Zagrosek,Carina Blomström Lundqvist,Claudio Borghi,Renata Cifkova,Rafael Ferreira,Jean-Michel Foidart,J Simon R Gibbs,Christa Gohlke-Baerwolf,Bulent Gorenek,Bernard Iung,Mike Kirby,Angela H E M Maas,João Morais,Petros Nihoyannopoulos,Petronella G. Pieper,Patrizia Presbitero,Jolien W. Roos-Hesselink,Maria Schaufelberger,Ute Seeland,Lucia Torracca,Jeroen J. Bax,A Auricchio,Helmut Baumgartner,Claudio Ceconi,Veronica Dean,Christi Deaton,Robert Fagard,Christian Funck-Brentano,David Hasdai,Arno W. Hoes,Juhani Knuuti,Philippe Kolh,Theresa McDonagh,Cyril Moulin,Don Poldermans,Bogdan Alexandru Popescu,Zeljko Reiner,Udo Sechtem,Per Anton Sirnes,Adam Torbicki,Alec Vahanian,Stephan Windecker,Carlos Aguiar,Nawwar Al-Attar,Angeles Alonso Garcia,Anna Antoniou,I M Coman,Uri Elkayam,Miguel Ángel Gómez-Sánchez,Nina Gotcheva,Denise Hilfiker-Kleiner,Róbert Gábor Kiss,Anastasia Kitsiou,Karen T S Konings,Gregory Y.H. Lip,Athanasios J. Manolis,Alexandre Mebaaza,Iveta Mintale,Marie Claude Morice,Barbara J.M. Mulder,Agnes Pasquet,Susanna Price,Silvia G. Priori,Maria J Salvador,Avraham Shotan,Candice K. Silversides,Sven O Skouby,Jörg Ingolf Stein,Pilar Tornos,Niels Vejlstrup,Fiona Walker,Carole A. Warnes +71 more