Journal ArticleDOI
Preliminary report on affective symptoms in the early stages of senile dementia of the Alzheimer type.
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The authors rated 30 probands with senile dementia of the Alzheimer type and 30 healthy controls for depression at the beginning of a longitudinal study and 1 year later.Abstract:
The authors rated 30 probands with senile dementia of the Alzheimer type and 30 healthy controls for depression at the beginning of a longitudinal study and 1 year later. Significant degrees of depression were not found in either group at either time.read more
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Journal ArticleDOI
Cornell Scale for Depression in Dementia.
TL;DR: The Cornell Scale for Depression in Dementia is introduced, a 19-item clinician-administered instrument that uses information from interviews with both the patient and a nursing staff member, a method suitable for demented patients.
Journal ArticleDOI
Profound Loss of Layer II Entorhinal Cortex Neurons Occurs in Very Mild Alzheimer’s Disease
Teresa Gomez-Isla,Joseph L. Price,Daniel W. McKeel,John C. Morris,John H. Growdon,Bradley T. Hyman +5 more
TL;DR: Stereological principles of neuron counting support the conclusion that a marked decrement of layer II neurons distinguishes even very mild AD from nondemented aging.
Journal ArticleDOI
Overview of depression and psychosis in Alzheimer's disease.
Robin E. Wragg,Dilip V. Jeste +1 more
TL;DR: The authors reviewed 30 studies on Alzheimer's disease to determine the prevalence and phenomenology of affective and psychotic symptoms in patients with this disorder and found Paranoid delusions was the most common psychotic symptoms reported.
Journal ArticleDOI
Very mild Alzheimer's disease: Informant‐based clinical, psychometric, and pathologic distinction from normal aging
John C. Morris,Daniel W. McKeel,Martha Storandt,Eugene H. Rubin,Joseph L. Price,Elizabeth A. Grant,Melvyn J. Ball,Leonard H. van den Berg +7 more
TL;DR: Findings indicate that even “questionable” dementia can be diagnostic for Alzheimer's disease, and because truly normal aging may be unaccompanied by neocortical senile plaques and neurofibrillary tangles, the presence of these lesions should suggest the possibility of clinically undetected Alzheimer's Disease.
Journal ArticleDOI
Neuropsychiatric aspects of multi-infarct dementia and dementia of the Alzheimer type
TL;DR: Depression and delusions were not deducted in patients with severe dementia, and hallucinations occurred in both diagnostic groups but were not common: one patient with DAT and one with MID had auditory hallucinations, and three patients with MIDHad visual hallucinations.