Journal ArticleDOI
Principles and recent developments in chelation treatment of metal intoxication.
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This article is published in Chemical Reviews.The article was published on 1999-09-08. It has received 330 citations till now.read more
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Book ChapterDOI
Potentially toxic elements, pollution and hair
TL;DR: In this article, a review of the effects of heavy metals and the role of hair analysis to monitor the health status of an individual is presented, focusing on the effect of exposure to heavy metals at the trace level.
Dissertation
Étude in vitro de la toxicité de l’uranium sur les cellules osseuses en vue de la recherche de nouveaux agents décorporants
TL;DR: In this paper, a 3,4,3-LI(1,2-HOPO) decorporant potentiel of l'uranium has been evaluated on the cellules of a lignee osteocytaire (MLO-A5).
Dissertation
To study the effect of salts and complexes of lead and arsenic metals on the status of thiols in blood components, pharmacological and toxicological perspectives
TL;DR: 1H NMR methods confirmed metal-thiol adducts to be the mechanism behind the GSH depletion in the presence of these metal compounds and detailed information about the changes in the chemical status of GSH was presented.
Journal ArticleDOI
Toward a ligand specific of Pb2+ with respect to the Zn2+ and Ca2+ cations: A track from quantum chemistry
TL;DR: In this paper, a ligand has emerged that could select Pb 2+ toward Zn 2+ and Ca 2+, an important point when designing new chelators usable in vivo as remediation agents against lead poisoning (saturnism).
Book ChapterDOI
Ecotoxicology of metals—sources, transport, and effects on the ecosystem
TL;DR: The most adverse impacts of metals (on populations) have been caused by organic tin compounds used in antifouling paints and aluminum mobilized by acid rain this paper , which may cause concerns for the health of human populations that rely heavily on their use as food items.
References
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Journal ArticleDOI
Hard and soft acids and bases
TL;DR: In this paper, the rate data for the generalized nucleophilic displacement reaction were reviewed, and the authors presented a method to estimate the rate of the generalized displacement reaction in terms of the number of nucleophiles.
Journal ArticleDOI
The long-term effects of exposure to low doses of lead in childhood. An 11-year follow-up report.
TL;DR: Exposure to lead in childhood is associated with deficits in central nervous system functioning that persist into young adulthood, and lead levels were inversely related to self-reports of minor delinquent activity.
Journal ArticleDOI
Drugs five years later. Cisplatin.
TL;DR: Although early trials showed marked gastrointestinal and renal toxicities, treatment-related morbidity has been significantly alleviated with modern antiemetic therapy and adequate pretreatment hydration.
Journal ArticleDOI
Penicillamine, a new oral therapy for Wilson's disease
TL;DR: A new form of oral treatment with dimethyl cysteine (penicillamine) is described, given in doses varying from 0.5 to 1.5 gm.
Journal ArticleDOI
Protection against tissue damage in vivo by desferrioxamine: what is its mechanism of action?
TL;DR: Desferrioxamine (deferoxamine) is an inhibitor of iron-dependent free radical reactions that has been used to investigate the role of such reactions in several animal model systems for human disease as mentioned in this paper.
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