Progesterone inhibits adenylate cyclase in Xenopus oocytes. Action on the guanine nucleotide regulatory protein.
S E Sadler,James L. Maller +1 more
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This article is published in Journal of Biological Chemistry.The article was published on 1981-06-25 and is currently open access. It has received 204 citations till now. The article focuses on the topics: Cyclase & Xenopus.read more
Citations
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Journal ArticleDOI
Nongenomic actions of steroid hormones
Ralf Lösel,Martin Wehling +1 more
TL;DR: This work has identified other responses to steroids that are much more rapid and take place in seconds or minutes, and they are not rare.
Journal ArticleDOI
The use of Xenopus oocytes for the study of ion channels.
TL;DR: Oocytes of the African frog Xenopus laevis have been exploited for the study of numerous aspects of ion channel function and regulation, such as the properties of several endogenous voltage-dependent channels and the involvement of second messengers in mediation of neurotransmitter-evoked membrane responses.
Journal ArticleDOI
Nongenomic Steroid Action: Controversies, Questions, and Answers
Ralf Lösel,Elisabeth Falkenstein,Martin Feuring,A. Schultz,Hanns-Christian Tillmann,K. Rossol‐Haseroth,Martin Wehling +6 more
TL;DR: Evidence is presented for and against both the participation of classic receptors, or proteins closely related to them, as well as for the involvement of yet poorly understood, novel membrane steroid receptors.
Journal ArticleDOI
Regulation of mouse oocyte meiotic maturation: Implication of a decrease in oocyte cAMP and protein dephosphorylation in commitment to resume meiosis
TL;DR: Mouse oocytes are reversibly inhibited from resuming meiotic maturation in vitro by cAMP phosphodiesterase inhibitors such as 3-isobutyl-1-methyl xanthine (IBMX) and cAMP analogs such as dibutyryl cAMP (dbcAMP) and a possible role cAMP may play in regulation of resumption of meiosis in mammals is discussed.
Journal ArticleDOI
Signal transduction by guanine nucleotide binding proteins
TL;DR: G-proteins also participate in other signal transduction pathways, notably that involving phosphoinositide breakdown, and are highlighted in this review.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
A Highly Sensitive Adenylate Cyclase Assay
TL;DR: The high sensitivity of this method permits detection of the small amounts of cyclic AMP formed at low enzyme concentrations or at early time points in kinetic studies.
Journal ArticleDOI
The role of hormone receptors and GTP-regulatory proteins in membrane transduction
TL;DR: Cell membrane receptors for hormones and neurotransmitters form oligomeric complexes with GTP-regulatory proteins and inhibit the latter from reacting with G TP, and this theory may apply generally to membrane signal transduction involving surface receptors.
Journal ArticleDOI
Biochemical properties of hormone-sensitive adenylate cyclase.
Elliott M. Ross,A. G. Gilman +1 more
Journal ArticleDOI
Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system
Dan Cassel,Thomas Pfeuffer +1 more
TL;DR: The results indicate that cholera toxin affects the adenylate cyclase system by catalyzing an ADP-ribosylation of the 42,000-M(r) component bearing the guanyl nucleotide regulatory site.
Related Papers (5)
Progesterone-stimulated meiotic cell division in Xenopus oocytes. Induction by regulatory subunit and inhibition by catalytic subunit of adenosine 3':5'-monophosphate-dependent protein kinase.
J L Maller,E G Krebs +1 more
Early effect of progesterone on levels of cyclic adenosine 3':5'-monophosphate in Xenopus oocytes.
J L Maller,F R Butcher,E G Krebs +2 more