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Open AccessJournal ArticleDOI

Prolonged viral shedding in pandemic influenza A(H1N1): clinical significance and viral load analysis in hospitalized patients

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TLDR
PVS was detected in 25% of hospitalized patients with pandemic 2009 influenza A(H1N1) and was strongly associated with immunosuppression and the need for MV and Diagnostic VL and viral clearance varied with the clinical course.
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This article is published in Clinical Microbiology and Infection.The article was published on 2011-08-01 and is currently open access. It has received 91 citations till now. The article focuses on the topics: Viral load & Influenza A virus.

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Antiviral agents for the treatment and chemoprophylaxis of influenza --- recommendations of the Advisory Committee on Immunization Practices (ACIP).

TL;DR: This report updates previous recommendations by CDC's Advisory Committee on Immunization Practices (ACIP) regarding the use of antiviral agents for the prevention and treatment of influenza and provides a summary of the effectiveness and safety of antivirus treatment medications.
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Early Corticosteroids in Severe Influenza A/H1N1 Pneumonia and Acute Respiratory Distress Syndrome

TL;DR: This study provides no evidence of a beneficial effect of corticosteroids in patients with ARDS secondary to influenza pneumonia, but suggests that very early corticosterone therapy may be harmful.
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Invasive pulmonary aspergillosis is a frequent complication of critically ill H1N1 patients: a retrospective study

TL;DR: The data suggest that use of CS 7 days before ICU admission is an independent risk factor for fungal superinfection, and point out the need for increased awareness of IPA, especially in those critically ill H1N1 patients already receiving CS.
References
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Journal ArticleDOI

The American-European Consensus Conference on ARDS: Definitions, mechanisms, relevant outcomes, and clinical trial coordination

TL;DR: The acute respiratory distress syndrome (ARDS), a process of nonhydrostatic pulmonary edema and hypoxemia associated with a variety of etiologies, carries a high morbidity, mortality, and financial cost.

Surviving sepsis campaign: international guidelines for the management of severe sepsis and septic shock: 2008

TL;DR: To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, the GRADE system was used to guide assessment of quality of evidence from high (A) to very low (D) and to determine the strength of recommendations.
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Mortality Associated With Influenza and Respiratory Syncytial Virus in the United States

TL;DR: Mortality associated with both influenza and RSV circulation disproportionately affects elderly persons, and influenza deaths have increased substantially in the last 2 decades, in part because of aging of the population, highlighting the need for better prevention measures, including more effective vaccines and vaccination programs for elderly persons.
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Influenza-associated hospitalizations in the United States.

TL;DR: Significant numbers of influenza-associated hospitalizations in the United States occur among the elderly, and the numbers of these hospitalizations have increased substantially over the last 2 decades due in part to the aging of the population.
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