Open AccessJournal Article
Prophylactic Cranial Irradiation in Extensive Small-Cell Lung Cancer
Reads0
Chats0
About:
This article is published in Journal of Evidence-based Medicine.The article was published on 2008-01-01 and is currently open access. It has received 167 citations till now. The article focuses on the topics: Prophylactic cranial irradiation.read more
Citations
More filters
Journal ArticleDOI
Epidemiology of Brain Metastases
TL;DR: The incidence of brain metastases is increasing with the availability of improved imaging techniques which aid early diagnosis, and effective systemic treatment regimens which prolong life, thus allowing cancer to disseminate to the brain.
Journal ArticleDOI
Prophylactic cranial irradiation versus observation in patients with extensive-disease small-cell lung cancer: a multicentre, randomised, open-label, phase 3 trial.
Toshiaki Takahashi,Takeharu Yamanaka,Takashi Seto,Hideyuki Harada,Hiroshi Nokihara,Hideo Saka,Makoto Nishio,Hiroyasu Kaneda,Koichi Takayama,Osamu Ishimoto,Koji Takeda,Hiroshige Yoshioka,Motoko Tachihara,Hiroshi Sakai,Koichi Goto,Nobuyuki Yamamoto +15 more
TL;DR: Prophylactic cranial irradiation is therefore not essential for patients with extensive-disease small-cell lung cancer with any response to initial chemotherapy and a confirmed absence of brain metastases when patients receive periodic MRI examination during follow-up.
Journal ArticleDOI
Effect of Lapatinib on the Outgrowth of Metastatic Breast Cancer Cells to the Brain
Brunilde Gril,Diane Palmieri,Julie L. Bronder,Jeanne M. Herring,Eleazar Vega-Valle,Lionel Feigenbaum,David J. Liewehr,Seth M. Steinberg,Maria Merino,Stephen D. Rubin,Patricia S. Steeg +10 more
TL;DR: Lapatinib is the first HER2-directed drug to be validated in a preclinical model for activity against brain metastases of breast cancer.
Journal ArticleDOI
Uptake of ANG1005, A Novel Paclitaxel Derivative, Through the Blood-Brain Barrier into Brain and Experimental Brain Metastases of Breast Cancer
Fancy Thomas,Kunal S Taskar,Vinay Rudraraju,Satyanarayana Goda,Helen R. Thorsheim,Julie A. Gaasch,Julie A. Gaasch,Rajendar K. Mittapalli,Diane Palmieri,Patricia S. Steeg,Paul R. Lockman,Quentin R. Smith +11 more
TL;DR: It is demonstrated that angiopep-2 paclitaxel conjugate shows significantly improved delivery to brain and brain metastases of breast cancer compared to free pac litaxel.
Journal ArticleDOI
NCCN guidelines® insights: Small cell lung cancer, version 2.2018 featured updates to the NCCN guidelines
Gregory P. Kalemkerian,Billy W. Loo,Wallace Akerley,Albert Attia,Michael F. Bassetti,Yanis Boumber,Roy H. Decker,M. Chris Dobelbower,Afshin Dowlati,Robert J. Downey,Charles Florsheim,Apar Kishor Ganti,John C. Grecula,Matthew A. Gubens,Christine L. Hann,James A. Hayman,Rebecca S. Heist,Marianna Koczywas,Robert E. Merritt,Nisha Mohindra,Julian R. Molina,Cesar A. Moran,Daniel Morgensztern,Saraswati Pokharel,David C. Portnoy,Deborah J. Rhodes,Chad G. Rusthoven,Rafael Santana-Davila,Charles C. Williams,Karin G. Hoffmann,Miranda Hughes +30 more
TL;DR: The NCCN Guidelines for Small Cell Lung Cancer (SCLC) address all aspects of disease management regarding immunotherapy, systemic therapy, and radiation therapy and new sections were added on "Signs and Symptoms of SCLC" and "Principles of Pathologic Review."
References
More filters
Journal ArticleDOI
Epidemiology of Brain Metastases
TL;DR: The incidence of brain metastases is increasing with the availability of improved imaging techniques which aid early diagnosis, and effective systemic treatment regimens which prolong life, thus allowing cancer to disseminate to the brain.
Journal ArticleDOI
Prophylactic cranial irradiation versus observation in patients with extensive-disease small-cell lung cancer: a multicentre, randomised, open-label, phase 3 trial.
Toshiaki Takahashi,Takeharu Yamanaka,Takashi Seto,Hideyuki Harada,Hiroshi Nokihara,Hideo Saka,Makoto Nishio,Hiroyasu Kaneda,Koichi Takayama,Osamu Ishimoto,Koji Takeda,Hiroshige Yoshioka,Motoko Tachihara,Hiroshi Sakai,Koichi Goto,Nobuyuki Yamamoto +15 more
TL;DR: Prophylactic cranial irradiation is therefore not essential for patients with extensive-disease small-cell lung cancer with any response to initial chemotherapy and a confirmed absence of brain metastases when patients receive periodic MRI examination during follow-up.
Journal ArticleDOI
Effect of Lapatinib on the Outgrowth of Metastatic Breast Cancer Cells to the Brain
Brunilde Gril,Diane Palmieri,Julie L. Bronder,Jeanne M. Herring,Eleazar Vega-Valle,Lionel Feigenbaum,David J. Liewehr,Seth M. Steinberg,Maria Merino,Stephen D. Rubin,Patricia S. Steeg +10 more
TL;DR: Lapatinib is the first HER2-directed drug to be validated in a preclinical model for activity against brain metastases of breast cancer.
Journal ArticleDOI
Uptake of ANG1005, A Novel Paclitaxel Derivative, Through the Blood-Brain Barrier into Brain and Experimental Brain Metastases of Breast Cancer
Fancy Thomas,Kunal S Taskar,Vinay Rudraraju,Satyanarayana Goda,Helen R. Thorsheim,Julie A. Gaasch,Julie A. Gaasch,Rajendar K. Mittapalli,Diane Palmieri,Patricia S. Steeg,Paul R. Lockman,Quentin R. Smith +11 more
TL;DR: It is demonstrated that angiopep-2 paclitaxel conjugate shows significantly improved delivery to brain and brain metastases of breast cancer compared to free pac litaxel.
Journal ArticleDOI
NCCN guidelines® insights: Small cell lung cancer, version 2.2018 featured updates to the NCCN guidelines
Gregory P. Kalemkerian,Billy W. Loo,Wallace Akerley,Albert Attia,Michael F. Bassetti,Yanis Boumber,Roy H. Decker,M. Chris Dobelbower,Afshin Dowlati,Robert J. Downey,Charles Florsheim,Apar Kishor Ganti,John C. Grecula,Matthew A. Gubens,Christine L. Hann,James A. Hayman,Rebecca S. Heist,Marianna Koczywas,Robert E. Merritt,Nisha Mohindra,Julian R. Molina,Cesar A. Moran,Daniel Morgensztern,Saraswati Pokharel,David C. Portnoy,Deborah J. Rhodes,Chad G. Rusthoven,Rafael Santana-Davila,Charles C. Williams,Karin G. Hoffmann,Miranda Hughes +30 more
TL;DR: The NCCN Guidelines for Small Cell Lung Cancer (SCLC) address all aspects of disease management regarding immunotherapy, systemic therapy, and radiation therapy and new sections were added on "Signs and Symptoms of SCLC" and "Principles of Pathologic Review."