Journal ArticleDOI
Protective effects of sinapic acid on cardiac hypertrophy, dyslipidaemia and altered electrocardiogram in isoproterenol-induced myocardial infarcted rats.
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TLDR
Pre- and co-treatment with sinapic acid ameliorated cardiac hypertrophy, dyslipidemia and elevated ST-segments in isoproterenol induced myocardial infarcted rats, and in vitro study revealed the potent antioxidant activity of sinapIC acid.About:
This article is published in European Journal of Pharmacology.The article was published on 2013-01-15. It has received 73 citations till now. The article focuses on the topics: Very low-density lipoprotein & High-density lipoprotein.read more
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Sinapic Acid and Its Derivatives as Medicine in Oxidative Stress-Induced Diseases and Aging
TL;DR: This minireview is an effort to summarize the available literature about pharmacokinetic, therapeutic, and protective potential of this versatile molecule in health related areas.
Journal ArticleDOI
Sinapic acid prevents hypertension and cardiovascular remodeling in pharmacological model of nitric oxide inhibited rats.
Thangarasu Silambarasan,Jeganathan Manivannan,Jeganathan Manivannan,Mani Krishna Priya,Natarajan Suganya,Suvro Chatterjee,Boobalan Raja +6 more
TL;DR: Results of in vitro study showed that, SA protects endothelial cells from oxidative stress and enhance the production of NO in a concentration dependent manner, suggesting that SA may have beneficial role in the treatment of hypertensive heart disease by attenuating fibrosis and oxidative stress through its antioxidant potential.
Journal ArticleDOI
Development of functional yogurt containing free and encapsulated echium oil, phytosterol and sinapic acid
Talita A. Comunian,Isabela Elias Chaves,Marcelo Thomazini,Izabel Cristina Freitas Moraes,Roselayne Ferro-Furtado,Inar Alves de Castro,Carmen Silvia Fávaro-Trindade +6 more
TL;DR: This work coencapsulate echium oil, phytosterols and sinapic acid (crosslinker/antioxidant), and incorporate the obtained microcapsules into yogurt, without compromising the rheological properties and physicochemical stability of the product.
Journal ArticleDOI
Isoproterenol-induced cardiac ischemia and fibrosis: Plant-based approaches for intervention
TL;DR: Molecular mechanism of various plant‐based interventions screened for cardioprotective effect in ISP‐induced cardiotoxicity, myocardial ischemia, and cardiac fibrosis is surveyed and their probable mechanistic profile is summarized.
Journal ArticleDOI
Molecular understanding of the protective role of natural products on isoproterenol-induced myocardial infarction: A review.
TL;DR: Promising results towards the amelioration of ISO-induced myocardial damage are highlighted, which suggest the direction for future research on natural products that could be used to treat MI.
References
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A simple method for the isolation and purification of total lipides from animal tissues.
TL;DR: In this paper, the authors described a simplified version of the method and reported the results of a study of its application to different tissues, including the efficiency of the washing procedure in terms of the removal from tissue lipides of some non-lipide substances of special biochemical interest.
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Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide.
P Fossati,L Prencipe +1 more
TL;DR: In this direct colorimetric procedure, serum triglycerides are hydrolyzed by lipase, and the released glycerol is assayed in a reaction catalyzed by glycersol kinase and L-alpha-glycerol-phosphate oxidase in a system that generates hydrogen peroxide.
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A new method for the direct determination of serum cholesterol.
TL;DR: Precision and reproducibility are demonstrated as well as the absorption characteristics of the purple color produced through the spectral range of 400 to 700 mμ.
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The role of lipid peroxidation and antioxidants in oxidative modification of LDL.
TL;DR: A comprehensive survey on the compositional properties of LDL relevant for its susceptibility to oxidation, on the mechanism and kinetics of LDL oxidation, and on the chemical and physico-chemical properties of HDL oxidized by exposure to copper ions is provided.
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An easy colorimetric micromethod for routine determination of free fatty acids in plasma
K. Falholt,B. Lund,W. Falholt +2 more
TL;DR: The extraction medium used contains chloroform-heptane-methanol mixture with a phosphate buffer gives a sufficient extraction of FFA from serum and contamination with interfering agents is avoided.