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Journal ArticleDOI

Quality of life and its predictors in patients with mild hypoxemia and chronic obstructive pulmonary disease

George P. Prigatano, +2 more
- 01 Aug 1984 - 
- Vol. 144, Iss: 8, pp 1613-1619
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TLDR
Degree of self-reported tension-anxiety was the single greatest predictor of both physical and psychosocial measures of quality of life and the Pao2 was not significantly related to quality-of-life measures in this patient group.
Abstract
• Measures of quality of life were obtained on 985 patients with mild hypoxemia and chronic obstructive pulmonary disease (COPD). A subsample of 100 patients were also given extensive neuropsychological and personality tests. Mildly hypoxemic COPD patients showed impairment in quality-of-life activities. They showed less impairment in physical function, compared with previous studies on COPD patients with hypoxemia, but about equal impairment in psychosocial function and dysphoric mood. Nonrelated health changes in life do not seem to account for these findings. Degree of self-reported tension-anxiety was the single greatest predictor of both physical and psychosocial measures of quality of life. Level of exercise completed, forced expiratory volume in 1 s, and neuropsychological status were significantly related to physical limitations, but not psychosocial functioning. The Pao2 was not significantly related to quality-of-life measures in this patient group. (Arch Intern Med1984;144:1613-1619)

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References
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Statistical methods

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The social readjustment rating scale

TL;DR: This report defines a method which achieves etiologic significance as a necessary but not sufficient cause of illness and accounts in part for the time of onset of disease and provides a quantitative basis for new epidemiological studies of diseases.
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The sickness impact profile: validation of a health status measure.

TL;DR: Differences among the correlations obtained for each criterion measure with SIP score are discussed in terms of the need for the development of criterion measures that can be expected to differentially relate to the constructs inherent in the SIP.
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