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Open AccessJournal ArticleDOI

Randomized clinical field trial on the effects of butaphosphan-cyanocobalamin and propylene glycol on ketosis resolution and milk production

TLDR
Results indicate that extended PG treatment is beneficial in decreasing blood BHB concentrations in more severely affected animals, and both B+C treatment and extendedPG treatment improved milk yield in animals with low blood glucose at the time of ketosis diagnosis.
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This article is published in Journal of Dairy Science.The article was published on 2017-05-01 and is currently open access. It has received 27 citations till now. The article focuses on the topics: Ketosis.

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Citations
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Journal ArticleDOI

Effects of sodium salicylate on glucose kinetics and insulin signaling in postpartum dairy cows.

TL;DR: Findings may be explained by enhanced hepatic insulin sensitivity leading to posttranscriptional suppression of gluconeogenesis and adaptive responses to decreased glucose supply in the pancreas and adipose tissue.
Journal ArticleDOI

Effects of Propylene Glycol on Negative Energy Balance of Postpartum Dairy Cows

TL;DR: The present review summarizes the recent research progress in the impacts of NEB in dairy cows and the properties of PG in alleviating NEB and reducing the risk of ketosis and the mechanism and effects of propylene glycol.
Journal ArticleDOI

Production-related metabolic disorders of cattle: ketosis, milk fever and grass staggers

TL;DR: The current available knowledge on various treatment strategies for ketosis, hypocalcaemia (milk fever), and hypomagnesaemia (grass staggers) in periparturient cattle is compared to provide current evidence-based treatment protocols for practising veterinarians.
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Aspects of transition cow metabolomics-Part I: Effects of a metaphylactic butaphosphan and cyanocobalamin treatment on the metabolome in liver, blood, and urine in cows with different liver metabotypes.

TL;DR: In this paper, an on-farm prospective 3-fold blinded randomized study involving 80 German Holstein cows was performed throughout 1 yr, where two groups received a treatment with butaphosphan and cyanocobalamin (BCC) at either the dosage recommended by the manufacturer or the double dosage (5 or 10 mL/100 kg of body weight).
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The effect of different treatments for early-lactation hyperketonemia on liver triglycerides, glycogen, and expression of key metabolic enzymes in dairy cattle

TL;DR: It is concluded that intravenous glucose and oral propylene glycol, commonly used treatments for ketosis in postpartum dairy cows, administered alone or in combination for a duration of 3 d did not have important beneficial or detrimental effects on selected indicators of liver composition and function in cows with hyperketonemia.
References
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Journal ArticleDOI

Partitioning of Nutrients During Pregnancy and Lactation: A Review of Mechanisms Involving Homeostasis and Homeorhesis

TL;DR: While not definitively established, roles for placental lactogen and prolactin are attractive possibilities in homeorhetic regulation of maternal tissues to support pregnancy and the initiation of lactaion, respectively.
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Impact of hyperketonemia in early lactation dairy cows on health and production.

TL;DR: Serum BHBA concentrations at or above 1,200 micromol/L in the first week following calving were associated with increased risks of subsequent displaced abomasum and metritis, and the best threshold for predicting subsequent risk of clinical ketosis from serum obtained during wk 1 and wk 2 postpartum was 1,400 micromols/L.
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Ruminant Adaptation to Negative Energy Balance: Influences on the Etiology of Ketosis and Fatty Liver

TL;DR: In this article, failure of hepatic gluconeogenesis to supply adequate glucose for lactation and body needs may be one cause of ketosis; however, poor feedback control of nonesterified fatty acid release from adipose tissue is another likely cause of fat liver failure.
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Feeding- and management-related diseases in the transition cow

TL;DR: Status-oriented strategies for optimising dairy cow health, reproduction and production are suggested that aims at securing a desirable status of epithelia, metabolism and immune function in different cells, tissues or organs through surveillance and health and production management based on indicators.
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Epidemiology of subclinical ketosis in early lactation dairy cattle

TL;DR: Results show that time of onset and BHBA concentration of first SCK-positive test are important indicators of individual cow performance and are associated with a decrease in milk production for the first 30 DIM.
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