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Open AccessJournal ArticleDOI

Invited Review: Pathology, Etiology, Prevention, and Treatment of Fatty Liver in Dairy Cows *

Gerd Bobe, +2 more
- 01 Oct 2004 - 
- Vol. 87, Iss: 10, pp 3105-3124
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TLDR
Preventing fatty liver by supplying cows with sufficient nutrients and a clean and health-promoting environment in the peripartal period would reduce production losses of cows more than would any treatment of fatty liver.
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This article is published in Journal of Dairy Science.The article was published on 2004-10-01 and is currently open access. It has received 725 citations till now. The article focuses on the topics: Fatty liver & Hepatic encephalopathy.

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The sheep genome illuminates biology of the rumen and lipid metabolism

Yu Jiang, +79 more
- 06 Jun 2014 - 
TL;DR: A genome for ewe and ewe Sheep-specific genetic changes underlie differences in lipid metabolism between sheep and other mammals, and may have contributed to the production of wool.
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Invited review: sensors to support health management on dairy farms.

TL;DR: This review has structured a total of 126 publications describing 139 sensor systems and compared them based on the 4 levels and found no systems with integrated decision support models have been found.
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Nutrition-induced ketosis alters metabolic and signaling gene networks in liver of periparturient dairy cows

TL;DR: Feed restriction and ketosis resulted in previously unrecognized alterations in gene network expression underlying key cellular functions and discrete metabolic events that might help explain well-documented physiological adaptations to reduced feed intake in early postpartum cows and, thus, provide molecular targets that might be useful in prevention and treatment of liver lipidosis andketosis.
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Physiological and pathological adaptations in dairy cows that may increase susceptibility to periparturient diseases and disorders

TL;DR: New techniques such as functional genomics, using cDNA or oligonucleotide microarrays, as well as proteomics and metabolomics, provide additional highthroughput tools to determine the effects of nutrition, management, or stressors on tissue function in development of disease.
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Nutrition, immune function and health of dairy cattle.

TL;DR: The main purpose of this review will be on the effect of physiological imbalance (PI) on immune function, and to give perspectives for prevention of diseases in the dairy cow through nutrition.
References
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Journal ArticleDOI

Biology of dairy cows during the transition period : the final frontier?

TL;DR: Estimates of the mixture of fuels constituting metabolizable energy in cows during the early postpartum period suggest that supply of amino acids and glucogenic compounds may be under proposed optima, whereas ketogenic and lipogenic compounds and long-chain fatty acids may be in excess.
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Physiological changes at parturition and their relationship to metabolic disorders.

TL;DR: Three basic physiological functions must be maintained during the periparturient period if disease is to be avoided: adaptation of the rumen to lactation diets that are high in energy density, maintenance of normocalcemia, and maintenance of a strong immune system.
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Etiology of Lipid-Related Metabolic Disorders in Periparturient Dairy Cows

TL;DR: Research to determine methods to reduce fatty acid delivery to the liver or to enhance hepatic export of very low density lipoprotein near calving is warranted because of increased fatty acid uptake by the liver, fatty acid esterification, and triglyceride storage.
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Antimicrobial Growth Promoters Used in Animal Feed: Effects of Less Well Known Antibiotics on Gram-Positive Bacteria

TL;DR: Since no susceptibility breakpoints are available for most of the antibiotics discussed, an alternative approach to the interpretation of MICs is presented and some pharmacokinetic data and information on the influence of these products on the intestinal flora are presented.
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Ruminant Adaptation to Negative Energy Balance: Influences on the Etiology of Ketosis and Fatty Liver

TL;DR: In this article, failure of hepatic gluconeogenesis to supply adequate glucose for lactation and body needs may be one cause of ketosis; however, poor feedback control of nonesterified fatty acid release from adipose tissue is another likely cause of fat liver failure.
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