Recent advances in the chemistry of 2-chloroquinoline-3-carbaldehyde and related analogs
TLDR
In this paper, a review highlights the recently cited research data in the literature on the chemistry of 2-chloroquinoline-3-carbaldehyde and related analogs and their applications over the period from 2013 to 2017.Abstract:
This review highlights the recently cited research data in the literature on the chemistry of 2-chloroquinoline-3-carbaldehyde and related analogs and their applications over the period from 2013 to 2017. It covers: synthesis of quinoline ring systems and reactions adopted to construct fused or binary quinoline-cord heterocyclic systems. The biological evaluation and the synthetic applications of the target compounds were illustrated.read more
Citations
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The antimicrobial potential and pharmacokinetic profiles of novel quinoline-based scaffolds: synthesis and in silico mechanistic studies as dual DNA gyrase and DHFR inhibitors
Mohamed H. El-Shershaby,Kamal M. El-Gamal,Ashraf H. Bayoumi,Khaled El-Adl,Khaled El-Adl,Mohamed Alswah,Hany E.A. Ahmed,Hany E.A. Ahmed,Ahmed A. Al-Karmalamy,Hamada S. Abulkhair +9 more
TL;DR: The resistance of pathogenic microbes to currently available antimicrobial agents has been considered a global alarming concern and is a major cause of concern for scientists.
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Rhodium-Catalyzed Selective C−H Bond Functionalization of Quinolines
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Recent advances in the chemistry of thieno[2,3-b]pyridines 1. Methods of synthesis of thieno[2,3-b]pyridines
TL;DR: The recent data (2007-2018) on the synthesis of thieno[2,3-b]pyridines are summarized and systematized in this paper.
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Synthesis, Structure, Chemical Stability, and In Vitro Cytotoxic Properties of Novel Quinoline-3-Carbaldehyde Hydrazones Bearing a 1,2,4-Triazole or Benzotriazole Moiety.
TL;DR: The most potent 2-(1H-benzotriazol-1-yl)-3-[2-(pyridin-2-yl)hydrazonomethyl]quinoline (5e) showed a cytostatic effect on the cancer cell lines, and seems to be leading compound for further development as anticancer agent.
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Recent update on antibacterial and antifungal activity of quinoline scaffolds.
TL;DR: The versatile derivatization of the quinoline moiety leading to significant antimicrobial potencies is discussed, considering the structure–activity relationship.
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