Journal ArticleDOI
Recovery of pregnancy mediated bone loss during lactation
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TLDR
At 1 year after delivery all but 7 women had returned to within 5% of the preconceptual value at the spine and trochanter but the recovery at the total hip was less complete and several women became transiently osteoporotic.About:
This article is published in Bone.The article was published on 2004-03-01. It has received 107 citations till now. The article focuses on the topics: Trochanter & Femoral neck.read more
Citations
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Journal ArticleDOI
Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery
TL;DR: This review addresses the current knowledge regarding maternal adaptations in mineral and skeletal homeostasis that occur during pregnancy, lactation, and post-weaning recovery and the impacts that these adaptations have on biochemical and hormonal parameters of mineralHomeostasis.
Journal ArticleDOI
Vitamin D supplementation in pregnancy: a systematic review.
Nicholas C. Harvey,Christopher Holroyd,Georgia Ntani,Kassim Javaid,Philip Cooper,Rebecca J Moon,Zoe Cole,Tannaze Tinati,Keith M. Godfrey,Elaine M. Dennison,Nick Bishop,Janis Baird,Cyrus Cooper +12 more
TL;DR: The evidence base is currently insufficient to support definite clinical recommendations regarding vitamin D supplementation in pregnancy, and modest positive relationships were identified between maternal 25(OH)D status and offspring birthweight, bone mass and serum calcium concentrations.
Journal ArticleDOI
Oxytocin is an anabolic bone hormone
Roberto Tamma,Graziana Colaianni,Ling Ling Zhu,Adriana DiBenedetto,Giovanni Greco,Gabriella Montemurro,Nicola Patano,Maurizio Strippoli,R. Vergari,Lucia Mancini,Silvia Colucci,Maria Grano,Roberta Faccio,Xuan Liu,Jianhua Li,Sabah Usmani,Marilyn Bachar,Itai Bab,Katsuhiko Nishimori,Larry J. Young,Christoph Buettner,Jameel Iqbal,Li Sun,Mone Zaidi,Alberta Zallone +24 more
TL;DR: Together, the complementary genetic and pharmacologic approaches reveal OT as a novel anabolic regulator of bone mass, with potential implications for osteoporosis therapy.
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Calcium and bone metabolism during pregnancy and lactation.
TL;DR: The present understanding of the adaptations in mineral metabolism that occur during pregnancy and lactation are reviewed, and recent evidence that the breast itself plays a central role in regulating the adaptations during lactation is focused on.
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Calcium and Bone Metabolism Disorders During Pregnancy and Lactation
TL;DR: Although some women may experience fragility fractures as a consequence of pregnancy or lactation, for most women, parity and lactation do not affect the long-term risks of low bone density, osteoporosis, or fracture.
References
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Journal ArticleDOI
Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group.
Steven R. Cummings,Michael C. Nevitt,Warren S. Browner,Katie L. Stone,Kathleen M. Fox,Kristine E. Ensrud,Jane A. Cauley,Dennis Black,Thomas M. Vogt +8 more
TL;DR: Women with multiple risk factors and low bone density have an especially high risk of hip fracture and maintaining body weight, walking for exercise, avoiding long-acting benzodiazepines, minimizing caffeine intake, and treating impaired visual function are among the steps that may decrease the risk.
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Epidemiology of osteoporosis and osteoporotic fractures
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Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells.
Lorenz C. Hofbauer,Sundeep Khosla,Colin R. Dunstan,David L. Lacey,Thomas C. Spelsberg,B. Lawrence Riggs +5 more
TL;DR: Estrogen enhancement of OPG secretion by osteoblastic cells may play a major role in the antiresorptive action of estrogen on bone.
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Factors Associated with Appendicular Bone Mass in Older Women
Douglas C. Bauer,Warren S. Browner,Jane A. Cauley,Eric S. Orwoll,Jean C. Scott,Dennis M. Black,Jo L. Tao,Steven R. Cummings +7 more
TL;DR: A wide variety of potential correlates of appendicular bone mass was examined in the Study of Osteoporotic Fractures, a large multicenter, community-based study of elderly women to determine what factors might contribute to osteopenia in older women.
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A longitudinal study of calcium homeostasis during human pregnancy and lactation and after resumption of menses.
Lorrene D. Ritchie,Ellen B. Fung,Bernard P. Halloran,Judith R. Turnlund,M D Van Loan,C E Cann,Janet C. King +6 more
TL;DR: Fetal calcium demand was met by increased maternal intestinal absorption; early breast-milk calcium was provided by maternal renal calcium conservation and loss of spinal trabecular bone, a loss that was recovered postmenses.