Journal ArticleDOI
Regulation of ribosomal RNA synthesis and its bearing on the bobbed phenotype in Drosophila melanogaster.
Jag Mohan,F.M. Ritossa +1 more
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TLDR
In spite of the reduced rate of synthesis in certain tissues, bobbed flies have been shown to have the same RNA/DNA ratio as phenotypically wild flies with different rDNA contents.About:
This article is published in Developmental Biology.The article was published on 1970-07-01. It has received 83 citations till now. The article focuses on the topics: Ribosomal RNA & RNA.read more
Citations
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BookDOI
The nucleolus and ribosome biogenesis
TL;DR: In this paper, the authors describe the structure of preribosomes and their role in the pre-rRNA precoding process, and discuss the role of RNA polymerases in the precoding.
Journal ArticleDOI
Location of the genes coding for 18S and 28S ribosomal RNA in the human genome
TL;DR: It was concluded that the probability of a chromosome being involved in the formation of a common nucleolus is not a simple function of its rDNA content and other possible factors are considered.
Journal ArticleDOI
Purification and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase II from the mouse plasmacytoma, MOPC 315.
TL;DR: Class III DNA-dependent RNA polymerases were purified from the mouse plasmacytoma, MOPC 315 by chromatography on DEAE-Sephadex and the specific activity of these enzymes was comparable to that reported for other purified eukaryoticRNA polymerases.
Journal ArticleDOI
Regulation of ribosomal rna gene multiplicity in drosophila melanogaster
TL;DR: Under appropriate genetic conditions, it appears that disproportionate rDNA replication can be generated at the level of both somatic and germ line cells.
Journal ArticleDOI
Amino acid starvation affects the initiation frequency of nucleolar RNA polymerase
TL;DR: The synthesis of ribosomal precursor RNA in mouse ascites nucleoli derived from cells starved for amino acids is compared with the activity of nucleoli from control cells cultivated in the presence of all amino acids and it is shown that deprivation of a single essential amino acid from the culture medium results in a drastic decrease of the RNA-forming capacity of the isolated nucleoli.
References
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Journal ArticleDOI
A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid
TL;DR: The present study arose from the observation that a more intense colour was sometimes produced if, instead of being heated at 1000 for 10 min., the reaction mixture was allowed to stand overnight at room temperature.
Book
Methods of Biochemical Analysis
TL;DR: The Radiation Inactivation Method as a Tool to Study Structure-Function Relationships in Proteins Immunoassay with Electrochemical Detection and Theory and Newer Technology Assays for Superoxide Dismutase are studied.
Journal ArticleDOI
A method for the determination of desoxyribonucleic acid, ribonucleic acid, and phosphoproteins in animal tissues.
TL;DR: The methods used at present for the determination of the higher nucleic acids in organs are based on certain color reactions of their carbohydrate components, but if the quantitative estimations of desoxyribonucleic acid and of ribon nucleic acid could be based on phosphorus determinations rather than on color tests of their carbohydrates components, these difficulties might be avoided.
Journal ArticleDOI
A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane
David Gillespie,Sol Spiegelman +1 more
TL;DR: An improved method for the formation of DNA—RNA hybrids is described, quantitatively more certain than annealing in liquid, since the competing DNA renaturation reaction is suppressed.
Related Papers (5)
A Molecular Explanation of the Bobbed Mutants of Drosophila as Partial Deficiencies of "Ribosomal" DNA
Localization of dna complementary to ribosomal rna in the nucleolus organizer region of drosophila melanogaster.
F. M. Ritossa,Sol Spiegelman +1 more
A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane
David Gillespie,Sol Spiegelman +1 more