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Relationship between radiographic features and bone mineral density in elderly men.

TLDR
The radiographic features of lumbar disc degeneration, anterior osteophytes, and end plate sclerosis were associated with an increase in BMD at the spine, and there was a strong negative correlation in terms of age at the femoral neck, though not at the backbone.
Abstract
Lumbar disc degeneration is characterised radiologically by the presence of osteophytes, endplate sclerosis, and disc space narrowing. Our study was designed to assess anterior lumbar osteophytes, disc space narrowing, end plate sclerosis, and bone mineral density (BMD) in the lumbar vertebrae and femoral neck of elderly men. A total of 1000 men, aged between 71 and 90 years, were invited to participate in the study. BMD was assessed at the spine and femoral neck using dual energy X-ray absorptiometry (DXA). We examined the relationship with the degree of lumbar spinal and femoral neck deformity by using the Z-score. Lateral and anterioposterior spinal radiographs were evaluated for features of lumbar disc degeneration. The observers consisted of a consultant physical therapist, a radiologist, and anatomists who together studied the series of radiographs. Anterior lumbar osteophytes (grade 0-3), end-plate sclerosis, and disc space narrowing (grade 0-2) were evaluated. The Pearson correlation test was used to determine the association between radiographic features, the lumbar mineral density (LBMD), and femoral neck mineral density (FNBMD). In all, 90.6% of lumbar vertebral levels showed evidence of anterior osteophytes, 87.5% showed evidence of end plate sclerosis, and 68.2% of disc space narrowing. Additionally, there was a strong negative correlation in terms of age at the femoral neck, though not at the spine. On the other hand, there was a significant correlation between osteophyte grade and end plate sclerosis at the spine. In our study, the radiographic features of lumbar disc degeneration, anterior osteophytes, and end plate sclerosis were associated with an increase in BMD at the spine.

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Aged-Related Changes in Body Composition and Association between Body Composition with Bone Mass Density by Body Mass Index in Chinese Han Men over 50-year-old

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Divergent Significance of Bone Mineral Density Changes in Aging Depending on Sites and Sex Revealed through Separate Analyses of Bone Mineral Content and Area

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References
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Journal Article

The relationship between spinal and peripheral osteoarthritis and bone density measurements.

TL;DR: The hypothesis that OA is negatively correlated with osteopenia is supported, as seen in this population, was not a generalized condition, but rather, was site specific.
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The Impact of Degenerative Conditions in the Spine on Bone Mineral Density and Fracture Risk Prediction

TL;DR: Osteophytes and endplate sclerosis have a considerable influence on spinal bone mass measurements in elderly postmenopausal women and affect the diagnostic ability of spinal scans to discriminate osteoporotic women, suggesting that in elderly women, unless the spine is radiologically clear of degenerative conditions, a peripheral measurement procedure should be considered an alternative for assessment of bone mineral content/ensity.
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Age estimation from the degree of osteophyte formation of vertebral columns in Japanese.

TL;DR: It was apparent that to know the degree of the osteophyte formation was useful in age estimation, and a significant correlation between the score value and age was recognized.
Journal ArticleDOI

Lack of association between lumbar disc degeneration and osteophyte formation in elderly japanese women with back pain.

TL;DR: It was shown that increases in osteophyte formation and BMD in the lumbar vertebrae are influenced by body weight and BMI, but did not correlate with disc area, which correlated inversely with BMD.
Journal ArticleDOI

Factors influencing lumbar spine bone mineral density assessment by dual-energy X-ray absorptiometry: Comparison with lumbar spinal radiogram

TL;DR: It is demonstrated that osteophyte formation, facet joint osteoarthritis, and vertebral fracture should be taken into account in the evaluation of bone mineral density by DXA in people in older age groups, since these conditions occur at a considerable rate in such subjects.
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