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Open AccessJournal ArticleDOI

Renal Physiology of Pregnancy

TLDR
The kidneys increase in length and volume, and physiologic hydronephrosis occurs in up to 80% of women, which is fundamental in caring for the pregnant patient.
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This article is published in Advances in Chronic Kidney Disease.The article was published on 2013-05-01 and is currently open access. It has received 385 citations till now. The article focuses on the topics: Pregnancy & Renal function.

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Citations
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Journal ArticleDOI

Pregnancy profiles in the common bottlenose dolphin (Tursiops truncatus): Clinical biochemical and hematological variations during healthy gestation and a successful outcome.

TL;DR: The normal reference ranges for each trimester established herein, will enable future identification of abnormalities occurring during pregnancy and help improve the understanding of factors potentially influencing a failed or successful pregnancy outcome.
Journal ArticleDOI

Psychotropic drug use in perinatal women with bipolar disorder.

TL;DR: The literature on the pharmacokinetics of lithium, lamotrigine, carbamazepine and atypical antipsychotics during pregnancy and postpartum are reviewed, recommendations for symptom and laboratory monitoring are proposed and recommendations for dose adjustments are presented.
Journal ArticleDOI

Renin-aldosterone system evaluation over four decades in an extended family with autosomal dominant pseudohypoaldosteronism due to a deletion in the NR3C2 gene.

TL;DR: Levels of aldosterone are a reliable marker to detect asymptomatic family members with renal PHA1 from an extended family spanning four generations, significantly mitigating the clinical course.
Journal ArticleDOI

Detection of distal ureteral stones in pregnancy using transvaginal ultrasound.

TL;DR: A utility of transvaginal ultrasound is suggested for the evaluation of the pregnant patient with 94% of distal stones being detected Transvaginal versus 29% transabdominally and there was significantly increased hydronephrosis and elevated RIs in patients with distal ureteral stones.
Journal ArticleDOI

Impaired renal reserve contributes to preeclampsia via the kynurenine and soluble fms–like tyrosine kinase 1 pathway

TL;DR: In this article , pregnant outbred mice with prior uninephrectomy and compared them with sham-operated littermates carrying both kidneys were found to show upregulation of l-kynurenine during pregnancy.
References
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Journal ArticleDOI

The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP)

TL;DR: The classification and diagnosis of the Hypertensive Disorders of Pregnancy: Statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP), Vol. 20, No. 1, pp. ix-xiv as mentioned in this paper.

Acog practice bulletin

Gynecologists
TL;DR: Much of the review will, of necessity, focus on general principles of critical care, extrapolating where possible to obstetric critical care.
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Temporal relationships between hormonal and hemodynamic changes in early human pregnancy.

TL;DR: Peripheral vasodilation occurs early in pregnancy prior to full placentation in association with renal vasodilated and activation of the renin-angiotensin-aldosterone system, suggesting that ANP increases in response to changes in intravasular volume.
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Renal hemodynamics and tubular function in normal human pregnancy

TL;DR: This paper attempts to describe the changes that occur during human pregnancy in renal hemodynamics and in certain aspects of tubular function, particularly the handling of uric acid and glucose.
Journal ArticleDOI

Serial changes in renal haemodynamics during normal human pregnancy

TL;DR: Effective renal plasma flow (ERPF) and glomerular filtration rate (GFR) and GFR/ERPF was significantly reduced during early pregnancy but rose to a value equivalent to the non‐pregnant during the third trimester.
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