Renal Physiology of Pregnancy
TLDR
The kidneys increase in length and volume, and physiologic hydronephrosis occurs in up to 80% of women, which is fundamental in caring for the pregnant patient.About:
This article is published in Advances in Chronic Kidney Disease.The article was published on 2013-05-01 and is currently open access. It has received 385 citations till now. The article focuses on the topics: Pregnancy & Renal function.read more
Citations
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Parity predicts biological age acceleration in post-menopausal, but not pre-menopausal, women
TL;DR: The findings suggest a link between reproductive function and physiological Dysregulation, and allude to possible compensatory mechanisms that buffer the effects of reproductive function on physiological dysregulation during a woman’s reproductive lifespan.
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Gestational diabetes insipidus: Diagnosis and management.
TL;DR: Differentiating the subtypes of DI during pregnancy is critical in order to provide optimal management of DI in pregnancy and avoid dehydration and hypernatremia in this vulnerable population.
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The Changing Landscape of Acute Kidney Injury in Pregnancy from an Obstetrics Perspective.
TL;DR: The factors that have contributed to the changing epidemiology of PR-AKI are scrutinized and challenges in the diagnosis and management of acute kidney injury (AKI) in pregnancy from an obstetrics perspective are discussed.
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Sexual Dimorphism in Drug Metabolism and Pharmacokinetics
Askhi M Valodara,Kaid Johar +1 more
TL;DR: Sex and gender-based differences in the metabolism of drugs exist at various levels and it may be due to the genomic and non-genomic action of sex hormones.
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Systemic Lupus Erythematosus Management in Pregnancy
Kathryn H. Dao,Bonnie L. Bermas +1 more
TL;DR: The addition of 81mg/d of aspirin at the end of the first trimester to reduce the risk of pre-eclampsia and the immunosuppressive azathioprine, tacrolimus and cyclosporine are compatible with pregnancy and lactation, mycophenolate mofetil (MMF)/mycophenolic acid are not.
References
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The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP)
TL;DR: The classification and diagnosis of the Hypertensive Disorders of Pregnancy: Statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP), Vol. 20, No. 1, pp. ix-xiv as mentioned in this paper.
Acog practice bulletin
TL;DR: Much of the review will, of necessity, focus on general principles of critical care, extrapolating where possible to obstetric critical care.
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Temporal relationships between hormonal and hemodynamic changes in early human pregnancy.
Arlene B. Chapman,William T. Abraham,Stacy Zamudio,Carolyn T. Coffin,Aicha Merouani,David A. Young,Ann M. Johnson,Fritz Osorio,Carol A. Goldberg,Lorna G. Moore,Thomas Dahms,Robert W. Schrier +11 more
TL;DR: Peripheral vasodilation occurs early in pregnancy prior to full placentation in association with renal vasodilated and activation of the renin-angiotensin-aldosterone system, suggesting that ANP increases in response to changes in intravasular volume.
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Renal hemodynamics and tubular function in normal human pregnancy
J. M. Davison,William Dunlop +1 more
TL;DR: This paper attempts to describe the changes that occur during human pregnancy in renal hemodynamics and in certain aspects of tubular function, particularly the handling of uric acid and glucose.
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Serial changes in renal haemodynamics during normal human pregnancy
TL;DR: Effective renal plasma flow (ERPF) and glomerular filtration rate (GFR) and GFR/ERPF was significantly reduced during early pregnancy but rose to a value equivalent to the non‐pregnant during the third trimester.