Renal Physiology of Pregnancy
TLDR
The kidneys increase in length and volume, and physiologic hydronephrosis occurs in up to 80% of women, which is fundamental in caring for the pregnant patient.About:
This article is published in Advances in Chronic Kidney Disease.The article was published on 2013-05-01 and is currently open access. It has received 385 citations till now. The article focuses on the topics: Pregnancy & Renal function.read more
Citations
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Journal ArticleDOI
Type 2 diabetes-associated genetic variants of FTO, LEPR, PPARg, and TCF7L2 in gestational diabetes in a Brazilian population
Mauren Isfer Anghebem-Oliveira,Mauren Isfer Anghebem-Oliveira,Bruna Rodrigues Martins,Dayane Alberton,Edneia A.S. Ramos,Geraldo Picheth,Fabiane Gomes de Moraes Rego +6 more
TL;DR: The studied polymorphisms were not associated with GDM in a Brazilian population and did not show significant differences between the groups (P > 0.05).
Journal ArticleDOI
Use of local anesthetics for dental treatment during pregnancy; safety for parturient
Ji Min Lee,Teo Jeon Shin +1 more
TL;DR: This review will focus on the maternal and fetal effects of local anesthetics widely used in dental treatment with consideration of the use of localAnesthetics during pregnancy.
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The prognostic role of serum uric acid levels in preeclampsia: A meta-analysis.
TL;DR: It is suggested that serum uric acid levels are increased in preeclampsia and can be used to predict disease severity and pregnancy complications.
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Dietary reference values for chloride.
Dominique Turck,Jacqueline Castenmiller,Stefaan De Henauw,Karen Ildico Hirsch-Ernst,John Kearney,Helle Katrine Knutsen,Alexandre Maciuk,Inge Mangelsdorf,Harry J McArdle,Carmen Pelaez,Kristina Pentieva,Alfonso Siani,Frank Thies,Sophia Tsabouri,Marco Vinceti,Peter Aggett,Susan J. Fairweather-Tait,Ambroise Martin,Hildegard Przyrembel,Agnès de Sesmaisons-Lecarré,Androniki Naska +20 more
TL;DR: Reference values for chloride can be set at values equimolar to the reference values for sodium for all population groups, and levels of chloride intake are considered to be safe and adequate for the general EU population under the consideration that the main dietary source of chloride Intake is sodium chloride.
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Effects of pregnancy on the pharmacokinetics of metformin
Michael Z. Liao,Shannon K. Flood Nichols,Mahmoud Ahmed,Shannon Clark,Gary D.V. Hankins,Steve N. Caritis,Raman Venkataramanan,David M. Haas,Sara K. Quinney,Laura S. Haneline,Alan T.N. Tita,Tracy Manuck,Joanne Wang,Kenneth E. Thummel,Linda Morris Brown,Zhaoxia Ren,Thomas R. Easterling,Mary F. Hebert +17 more
TL;DR: Pregnant women undergo physiological changes that alter drug disposition that suggest that pregnancy lowers metformin concentrations, potentially affecting efficacy and safety and expands the mechanistic understanding of pharmacokinetic changes across the dosage range.
References
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The classification and diagnosis of the hypertensive disorders of pregnancy: statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP)
TL;DR: The classification and diagnosis of the Hypertensive Disorders of Pregnancy: Statement from the International Society for the Study of Hypertension in Pregnancy (ISSHP), Vol. 20, No. 1, pp. ix-xiv as mentioned in this paper.
Acog practice bulletin
TL;DR: Much of the review will, of necessity, focus on general principles of critical care, extrapolating where possible to obstetric critical care.
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Temporal relationships between hormonal and hemodynamic changes in early human pregnancy.
Arlene B. Chapman,William T. Abraham,Stacy Zamudio,Carolyn T. Coffin,Aicha Merouani,David A. Young,Ann M. Johnson,Fritz Osorio,Carol A. Goldberg,Lorna G. Moore,Thomas Dahms,Robert W. Schrier +11 more
TL;DR: Peripheral vasodilation occurs early in pregnancy prior to full placentation in association with renal vasodilated and activation of the renin-angiotensin-aldosterone system, suggesting that ANP increases in response to changes in intravasular volume.
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Renal hemodynamics and tubular function in normal human pregnancy
J. M. Davison,William Dunlop +1 more
TL;DR: This paper attempts to describe the changes that occur during human pregnancy in renal hemodynamics and in certain aspects of tubular function, particularly the handling of uric acid and glucose.
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Serial changes in renal haemodynamics during normal human pregnancy
TL;DR: Effective renal plasma flow (ERPF) and glomerular filtration rate (GFR) and GFR/ERPF was significantly reduced during early pregnancy but rose to a value equivalent to the non‐pregnant during the third trimester.