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Response-adaptive randomization: an overview of designs and asymptotic theory
TLDR
The authors provide an overview of important research works on response-adaptive randomization completed in the past decades, and provide a survey of the most relevant work in this area. But,Abstract:
In this paper we provide an overview of important research works on response-adaptive randomization completed in the past decades.read more
Citations
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Proceedings ArticleDOI
Asymptotics in randomized urn models
Zhidong Bai,Feifang Hu +1 more
TL;DR: In this article, the authors studied a very general urn model stimulated by designs in clinical trials, where the number of balls of different types added to the urn at trial n depends on a random outcome directed by the composition at trials 1,2,…,n−1.
Proceedings ArticleDOI
Asymptotic properties of adaptive designs for clinical trials with delayed response
TL;DR: In this article, the authors derived the limiting distribution of the urn composition under staggered entry and delayed response for adaptive clinical trials using a generalized Friedman's urn design, and showed that maximum likelihood estimators from such a trial have the usual asymptotic properties.
Dissertation
Group-Sequential Response-Adaptive Designs for Comparing Several Treatments
TL;DR: The adaptive design generalised to multi-arm clinical trials is studied and the application of the adaptive design to censored survival responses is investigated and different optimal response-adaptive randomised procedures compared.
References
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Journal ArticleDOI
On the likelihood that one unknown probability exceeds another in view of the evidence of two samples
Journal ArticleDOI
Some aspects of the sequential design of experiments
TL;DR: The authors proposed a theory of sequential design of experiments, in which the size and composition of the samples are not fixed in advance but are functions of the observations themselves, which is a major advance.
Book
Group Sequential Methods with Applications to Clinical Trials
TL;DR: A short history of sequential and group sequential methods can be found in this paper, where the authors present a road map for the application of two-sided tests for comparing two treatments with normal response of known variance.
Journal ArticleDOI
Forcing a sequential experiment to be balanced
TL;DR: In this paper, a new method of assigning the subjects which tends to balance the experiment, but at the same time is not over vulnerable to various common forms of experimental bias is discussed.
Journal ArticleDOI
Extracorporeal circulation in neonatal respiratory failure: a prospective randomized study.
Robert H. Bartlett,Dietrich W. Roloff,Richard G. Cornell,Andrews Af,Peter W. Dillon,Joseph B. Zwischenberger +5 more
TL;DR: In this paper, a prospective controlled randomized study of the use of extracorporeal membrane oxygenation to treat newborns with respiratory failure was carried out using the randomized play-the-winner statistical method, where the chance of randomly assigning an infant to one treatment or the other is influenced by the outcome of treatment of each patient in the study.