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Journal ArticleDOI

Reversal with sugammadex in the absence of monitoring did not preclude residual neuromuscular block.

Yoshifumi Kotake, +7 more
- 11 Jun 2013 - 
- Vol. 117, Iss: 2, pp 345-351
TLDR
This study demonstrated that the risk of TOFR <0.9 after tracheal extubation after sugammadex remains as high as 9.4% in a clinical setting in which neuromuscular monitoring (objective or subjective) was not used.
Abstract: 
BACKGROUND:In Japan, routine clinical care does not normally involve the use of a monitoring device to guide the administration of neuromuscular blocking drugs or their antagonists. Although most previous reports demonstrate that sugammadex offers more rapid and reliable antagonism from rocuronium-i

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Citations
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Journal ArticleDOI

Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery, part 2: consensus statement for anaesthesia practice

Aarne Feldheiser, +17 more
- 01 Mar 2016 - 
TL;DR: Clinical considerations and recommendations for anaesthetic practice in patients undergoing gastrointestinal surgery with an Enhanced Recovery after Surgery (ERAS) programme are proposed.
Journal ArticleDOI

Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study.

Eva Kirmeier, +865 more
- 01 Feb 2019 - 
TL;DR: It is shown that the use of neuromuscular blocking drugs in general anaesthesia is associated with an increased risk of postoperative pulmonary complications, and Anaesthetists must balance the potential benefits of neurmuscular blockade against the increasedrisk of postoperatively pulmonary complications.
Journal ArticleDOI

Consensus Statement on Perioperative Use of Neuromuscular Monitoring.

Mohamed Naguib, +8 more
- 01 Nov 2017 - 
TL;DR: A panel of clinician scientists with expertise in neuromuscular blockade (NMB) monitoring was convened with a charge to prepare a consensus statement on indications for and proper use of such monitors, and a set of recommendations for quantitative NMB monitoring standards are offered.
Journal ArticleDOI

Current Status of Neuromuscular Reversal and Monitoring: Challenges and Opportunities.

Sorin J. Brull, +1 more
- 01 Jan 2017 - 
TL;DR: Objective measurement (a train-of-four ratio greater than 0.90) is the only method to determine appropriate timing of tracheal extubation and ensure normal muscle function and patient safety.
Journal ArticleDOI

Effects of sugammadex on incidence of postoperative residual neuromuscular blockade: a randomized, controlled study

B. Brueckmann, +14 more
- 01 Nov 2015 - 
TL;DR: After abdominal surgery, sugammadex reversal eliminated residual neuromuscular blockade in the PACU, and shortened the time from start of study medication administration to the time the patient was ready for discharge from the operating room.
References
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Journal ArticleDOI

Prediction of Postoperative Pulmonary Complications in a Population-based Surgical Cohort

Jaume Canet, +9 more
- 01 Dec 2010 - 
TL;DR: The risk index based on seven objective, easily assessed factors has excellent discriminative ability and can be used to assess individual risk of PPC and focus further research on measures to improve patient care.
Journal ArticleDOI

Residual neuromuscular blockade and critical respiratory events in the postanesthesia care unit

Glenn S. Murphy, +5 more
- 01 Jul 2008 - 
TL;DR: It is suggested that incomplete neuromuscular recovery is an important contributing factor in the development of adverse respiratory events in the PACU, which was absent in control patients without CREs.
Journal ArticleDOI

Residual paralysis in the PACU after a single intubating dose of nondepolarizing muscle relaxant with an intermediate duration of action.

Bertrand Debaene, +3 more
- 01 May 2003 - 
TL;DR: After a single dose of intermediate-duration muscle relaxant and no reversal, residual paralysis is common, even more than 2 h after the administration of muscle relaxants, as shown in patients enrolled in this study.
Journal ArticleDOI

Residual neuromuscular block: lessons unlearned. Part I: definitions, incidence, and adverse physiologic effects of residual neuromuscular block.

Glenn S. Murphy, +1 more
- 04 May 2010 - 
TL;DR: Recovering incomplete neuromuscular recovery during the early postoperative period may result in acute respiratory events, unpleasant symptoms of muscle weakness, longer postanesthesia care unit stays, delays in tracheal extubation, and an increased risk of postoperative pulmonary complications.
Journal ArticleDOI

Reversal of profound rocuronium-induced blockade with sugammadex: a randomized comparison with neostigmine.

R Kevin Jones, +3 more
- 01 Nov 2008 - 
TL;DR: Recovery from profound rocuronium-induced neuromuscular blockade was significantly faster with sugammadex versus with neostigmine, suggesting that sugamadex has a unique ability to rapidly reverse profound roCuronium neuromUScular blockade.
Related Papers (5)

Residual neuromuscular blockade and critical respiratory events in the postanesthesia care unit

Glenn S. Murphy, +5 more
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A survey of current management of neuromuscular block in the United States and Europe.

Mohamed Naguib, +5 more
- 01 Jul 2010 - 

Residual neuromuscular block: lessons unlearned. Part I: definitions, incidence, and adverse physiologic effects of residual neuromuscular block.

Glenn S. Murphy, +1 more
- 04 May 2010 - 

Residual neuromuscular block is a risk factor for postoperative pulmonary complications: A prospective, randomised, and blinded study of postoperative pulmonary complications after atracurium, vecuronium and pancuronium

H. Berg, +6 more
- 01 Oct 1997 - 

Reversal of profound rocuronium-induced blockade with sugammadex: a randomized comparison with neostigmine.

R Kevin Jones, +3 more
- 01 Nov 2008 -