Journal ArticleDOI
Role of NADPH oxidase/ROS in pro-inflammatory mediators-induced airway and pulmonary diseases.
I-Ta Lee,Chuen-Mao Yang +1 more
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TLDR
Mechanisms of NADPH oxidase/ROS in the expression of inflammatory target proteins involved in airway and lung diseases are discussed.About:
This article is published in Biochemical Pharmacology.The article was published on 2012-09-01. It has received 343 citations till now. The article focuses on the topics: NADPH oxidase & Oxidative stress.read more
Citations
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Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease
TL;DR: A greater fundamental understanding of the mechanisms that preserve protein folding homeostasis and redox status will provide new information toward the development of novel therapeutics for many human diseases.
Journal ArticleDOI
Role of Redox Signaling in Neuroinflammation and Neurodegenerative Diseases
Hsi-Lung Hsieh,Chuen-Mao Yang +1 more
TL;DR: The mechanisms underlying the intracellular signaling pathways, especially ROS, involved in the expression of several inflammatory proteins induced by proinflammatory factors in brain resident cells are discussed.
Journal ArticleDOI
Exercise Modulates Oxidative Stress and Inflammation in Aging and Cardiovascular Diseases
Nada A Sallam,Ismail Laher +1 more
TL;DR: It is important to note that the effects of exercise vary depending on the type, intensity, frequency, and duration of exercise as well as on the individual's characteristics; therefore, the development of personalized exercise programs is essential.
Journal ArticleDOI
Cellular stress response and innate immune signaling: integrating pathways in host defense and inflammation.
TL;DR: The regulation of innate immune cell activation by cell stress pathways is described, detailed descriptions of the types of stress response proteins and their crosstalk with immune signaling intermediates that are essential in host defense are presented, and the relevance of these interactions in diseases characteristic of aberrant immune responses is illustrated.
Journal ArticleDOI
Antioxidant enzymes regulation in plants in reference to reactive oxygen species (ROS) and reactive nitrogen species (RNS)
Dhriti Kapoor,Simranjeet Singh,Vijay Kumar,Romina Romero,Ram Prasad,Ram Prasad,Joginder Singh +6 more
TL;DR: The novel findings of cellular processes induced by ROS and RNS are reviewed and the functions of cellular endogenous antioxidant systems as well as natural anti-oxidative compounds in plants are recapitulate to facilitate the illustration of the imperative role of antioxidants in prevention against oxidative stress.
References
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Journal ArticleDOI
Free Radicals in the Physiological Control of Cell Function
TL;DR: There is growing evidence that aging involves, in addition, progressive changes in free radical-mediated regulatory processes that result in altered gene expression.
Journal ArticleDOI
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
Karen Bedard,Karl-Heinz Krause +1 more
TL;DR: This review summarizes the current state of knowledge of the functions of NOX enzymes in physiology and pathology.
Journal ArticleDOI
Vascular endothelial growth factor (VEGF) and its receptors
TL;DR: Recent developments that have widened considerably the understanding of the mechanisms that control V EGF production and VEGF signal transduction are focused on and recent studies that have shed light on the mechanisms by which VEGf regulates angiogenesis are reviewed.
Journal ArticleDOI
Cell transformation by the superoxide-generating oxidase Mox1
Young Ah Suh,Rebecca S. Arnold,Bernard Lassègue,Jing Shi,Xiang Xi Xu,Dan Sorescu,Andrew B. Chung,Kathy K. Griendling,J. David Lambeth +8 more
TL;DR: The cloning of mox1 is described, which encodes a homologue of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox, which is expressed in colon, prostate, uterus and vascular smooth muscle, but not in peripheral blood leukocytes.
Journal ArticleDOI
Oxidative stress and regulation of glutathione in lung inflammation
Irfan Rahman,William MacNee +1 more
TL;DR: The redox control and involvement of nuclear factor-kappaB and activator protein-1 in the regulation of cellular glutathione and gamma-glutamylcysteine synthetase under conditions of oxidative stress and inflammation are described.
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The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
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