SARS-CoV-2 transmission and control in a hospital setting: an individual-based modelling study
Qimin Huang,Anirban Mondal,Xiaobing Jiang,Mary Ann Horn,Fei Fan,Peng Fu,Xuan Wang,Hongyang Zhao,Martial L. Ndeffo-Mbah,David Gurarie +9 more
TLDR
In this article, the authors developed an individual-based model for COVID-19 transmission in a hospital setting and calibrated the model using data of a COVID19 outbreak in a unit in Wuhan.Abstract:
Development of strategies for mitigating the severity of COVID-19 is now a top public health priority. We sought to assess strategies for mitigating the COVID-19 outbreak in a hospital setting via the use of non-pharmaceutical interventions. We developed an individual-based model for COVID-19 transmission in a hospital setting. We calibrated the model using data of a COVID-19 outbreak in a hospital unit in Wuhan. The calibrated model was used to simulate different intervention scenarios and estimate the impact of different interventions on outbreak size and workday loss. The use of high-efficacy facial masks was shown to be able to reduce infection cases and workday loss by 80% (90% credible interval (CrI): 73.1-85.7%) and 87% (CrI: 80.0-92.5%), respectively. The use of social distancing alone, through reduced contacts between healthcare workers, had a marginal impact on the outbreak. Our results also indicated that a quarantine policy should be coupled with other interventions to achieve its effect. The effectiveness of all these interventions was shown to increase with their early implementation. Our analysis shows that a COVID-19 outbreak in a hospital's non-COVID-19 unit can be controlled or mitigated by the use of existing non-pharmaceutical measures.read more
Citations
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SARS-CoV-2 outbreaks in hospitals and long-term care facilities in Germany: a national observational study
Beneditta Suwono,Annika Steffen,Birgitta Schweickert,Viktoria Schönfeld,M. Brandl,Mirco Sandfort,Niklas Willrich,Tim Eckmanns,Sebastian Haller +8 more
TL;DR: In this article , the authors analyzed the frequency and size of SARS-CoV-2 outbreaks in hospitals and LTCFs have altered since the beginning of the pandemic, in particular since the start of the vaccination campaign.
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A multi-scale agent-based model of infectious disease transmission to assess the impact of vaccination and non-pharmaceutical interventions: The COVID-19 case
TL;DR: In this article, a multi-scale agent-based model is proposed to investigate the infectious disease propagation between cities and within a city using the knowledge from person-to-person transmission.
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Using simulation modelling and systems science to help contain COVID‐19: A systematic review
TL;DR: In this article , the authors systematically review applications of three simulation approaches, that is, system dynamics model (SDM), agent-based model (ABM), and their hybrids in COVID•19 research and identify theoretical and application innovations in public health.
Journal ArticleDOI
Nosocomial transmission clusters and lineage diversity characterized by SARS-CoV-2 genomes from two large hospitals in Paris, France, in 2020
Valentin Leducq,Aude Jary,Antoine Bridier-Nahmias,Lena Daniel,Karen Zafilaza,Florence Damond,Valerie Goldstein,Audrey Duval,François Blanquart,Vincent Calvez,Diane Descamps,Anne-Geneviève Marcelin,Benoit Visseaux +12 more
TL;DR: In this article , a tree-based phylogenetic clustering method and epidemiological data were used to investigate suspected nosocomial transmission clusters in SARS-CoV-2.
Posted ContentDOI
Individual-based modeling of COVID-19 transmission in college communities
TL;DR: In this article, the authors developed a flexible computational framework to model the spread and control of COVID-19 on a residential college campus and explored the relative contribution of classroom, dorm, and social activities to disease transmission.
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