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Selenium and Glutathione Peroxidase Distribution in Bovine Semen and Selenium-75 Retention by the Tissues of the Reproductive Tract in the Bull

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This article is published in Biology of Reproduction.The article was published on 1979-03-01 and is currently open access. It has received 65 citations till now. The article focuses on the topics: Glutathione peroxidase & GPX5.

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Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa. Superoxide dismutase as major enzyme protectant against oxygen toxicity.

TL;DR: The results suggest that superoxide dismutase plays the major role in protecting human spermatozoa against lipid peroxidation, and the superoxide Dismutase activity of a fresh sperm sample appears to be a good predictor of the lifetime (up to the complete loss of motility) of that particular sample, and so may prove useful in semen analysis.
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Role of glutathione peroxidase in protecting mammalian spermatozoa from loss of motility caused by spontaneous lipid peroxidation.

TL;DR: A mechanism for spontaneous lipid peroxidation in mammalian sperm is postulated which involves reaction of lipid hydroperoxide and O2 as the rate-determining step and the key intermediate is lipid hydro peroxide generated by a chain reaction initiated by and utilizing superoxide.
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Levels of antioxidant defenses are decreased in bovine spermatozoa after a cycle of freezing and thawing.

TL;DR: It is found that bovine spermatozoa are poorly adapted to metabolize the toxic hydrogen peroxide and the involvement of an oxidative stress during a freeze/thaw cycle is consistent with the hypothesis that ROS generated during such a cycle are detrimental to sperm function.
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Biochemistry of the induction and prevention of lipoperoxidative damage in human spermatozoa

TL;DR: Human spermatozoa appear to have enough anti-lipoperoxidative defensive capacity for lifetimes long enough for fertilization but still short enough for ready removal from the female reproductive tract in good time.
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Recent Developments in the Roles of Vitamins and Minerals in Reproduction

TL;DR: The interface between nutritional science and reproductive physiology provides considerable potential for optimizing reproductive efficiency in dairy cattle and it attempts to provide a basis for further investigation of specific mechanisms by which reproductive function is affected.
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