Journal ArticleDOI
Sequential mechanism of atrial natriuretic peptide secretion in isolated perfused rabbit atria.
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It was shown in the present experiment that the secretion of immunoreactive (ir) ANP occurs coincidently with a translocation of extracellular space marker (3-H)-inulin in the isolated perfused rabbit atria.About:
This article is published in Biochemical and Biophysical Research Communications.The article was published on 1990-10-30. It has received 23 citations till now. The article focuses on the topics: Atrial natriuretic peptide & Atrial volume receptors.read more
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Journal ArticleDOI
Extracellular fluid translocation in perfused rabbit atria: implication in control of atrial natriuretic peptide secretion.
TL;DR: It is suggested that atrial stretch and release may play a role in driving fluid flow within the interstitium and fluid translocation out of the interSTitium in response to atrial distension and reduction.
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Glibenclamide suppresses stretch-activated ANP secretion: involvements of K+ATP channels and L-type Ca2+ channel modulation.
TL;DR: It is suggested that glibenclamide suppresses atrial release of ANP by blocking K+ATP channels and increasing Ca2+ influx and that the K+ ATP channels are associated with the regulation of the mechanically activated atrial natriuretic peptide secretion from the atria.
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Angiotensin-(1–7) stimulates high atrial pacing-induced ANP secretion via Mas/PI3-kinase/Akt axis and Na+/H+ exchanger
TL;DR: Results suggest that ANG-(1-7) increased ANP secretion at high atrial pacing via the Mas/PI3K/Akt pathway and the activation of Na(+)/H(+) exchanger-1 and CaMKII and Angiotensin decreased cardiac hypertrophy which might be mediated by ANP.
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Distinct roles for L- and T-type Ca2+ channels in regulation of atrial ANP release
Jin Fu Wen,Xun Cui,Jin Sub Ahn,Suhn Hee Kim,Kyung Hwan Seul,Sung Zoo Kim,Young Kyung Park,Ho Sub Lee,Kyung Woo Cho +8 more
TL;DR: The results suggest that activation of L- and T-type Ca(2+) channels elicits opposite effects on atrial myocytic release of ANP.
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Effect of ryanodine on atrial natriuretic peptide secretion by contracting and quiescent rat atrium
TL;DR: The present results support the notion that intracellular Ca2+ transients from the intrACEllular stores are essential for stretch-stimulated ANP secretion, independently from excitation and contraction, and confirm that the principal stimulus for AnP secretion in response to atrial distension is the stretch of myocytes.
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Journal ArticleDOI
Atrial natriuretic factor—a circulating hormone stimulated by volume loading
TL;DR: A sensitive and specific radio-immunoassay for atrial natriuretic factor and its stimulation on volume loading is described and its effects on salt loading and blood volume are described.
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Release of atrial natriuretic peptide by atrial distension.
TL;DR: A heterologous radioimmunoassay was used to measure the concentration of immunoreactive atrial natriuretic peptide (iANP) in plasma from the femoral artery of eight chloralose anaesthetized dogs finding that release of iANP depends on direct stretch of the atrium rather than on a reflex involving left atrial receptors.
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Plasma concentration of atrial natriuretic factor in a patient with paroxysmal atrial tachycardia.
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Release of atriopeptin in the rat by vasoconstrictors or water immersion correlates with changes in right atrial pressure
TL;DR: It is found that the release of atriopeptin directly correlated with changes in right atrial pressure in anesthetized, water-immersed rats, suggesting that plasma atriopesin most closely correlates with right atrian pressure.
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Immunoreactive atrial natriuretic factor (IR-ANF) in human plasma
Jolanta Gutkowska,Martial G. Bourassa,Denis-Claude Roy,Gaétan Thibault,Raul Garcia,Marc Cantin,Jacques Genest +6 more
TL;DR: A direct radioimmunoassay for ANF in human plasma was developed and in two patients who underwent atrial pacing an increase of about 100 percent in circulating IR-ANF was observed.