Journal ArticleDOI
Serum Galectin 7 is Not Useful to Predict Abortion in the First Trimester.
Fulya Cagli,Gulsum Uysal,Leyla Öz,Hatice Akkaya,Hüseyin Aksoy,Eda Ulku Karakilic,Gökhan Açmaz +6 more
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Serum galectin-7 was not useful for predicting prognosis in TA and should not be considered as a prognostic value, according to the authors.Abstract:
Objective: Galectins are animal lectins that bind to surface glycoproteins expressed at the fetal-maternal interface. The aim of this prospective case–control study was to investigate the possible ...read more
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Pregnancy Galectinology: Insights Into a Complex Network of Glycan Binding Proteins
Sandra M. Blois,Sandra M. Blois,Gabriela S. Dveksler,Gerardo R. Vasta,Nancy Freitag,Véronique Blanchard,Gabriela Barrientos +6 more
TL;DR: The relevance of galectin-glycan interactions as potential therapeutic targets in pregnancy disorders is discussed and the importance of angiogenesis during decidualization and in placenta formation is discussed.
References
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Journal ArticleDOI
Paternal age and maternal age are risk factors for miscarriage; results of a multicentre European study
TL;DR: Both maternal age and paternal age effects on miscarriage risk are investigated to provide insight into this frequent reproductive failure and it is found that the risk of miscarriage was higher if the woman was aged > or = 35 years, as has already been reported in a number of studies.
Journal ArticleDOI
Critical growth factors and signalling pathways controlling human trophoblast invasion
TL;DR: Current understanding of growth factors and signal transduction pathways regulating human trophoblast invasion/migration is summarized and insights into novel mechanisms involved in the particular differentiation process are given.
Journal ArticleDOI
Galectin fingerprinting in human endometrium and decidua during the menstrual cycle and in early gestation.
TL;DR: Cycle-dependent expression of galectin-1 in stromal cells and galECTin-3 in epithelial cells suggest these lectins to be involved in the regulation of different endometrial cellular functions.
Journal ArticleDOI
The clinical significance of ultrasonographically detected subchorionic hemorrhages
TL;DR: The presence of an ultransonographically detected subchorionic hemorrhage increases the risk of miscarriage, stillbirth, abruptio placentae, and preterm labor.
Journal ArticleDOI
Galectin-1 influences trophoblast immune evasion and emerges as a predictive factor for the outcome of pregnancy
Irene Tirado-González,Nancy Freitag,Gabriela Barrientos,Valerie Shaikly,Olga Nagaeva,Magnus Strand,Lennart Kjellberg,Burghard F. Klapp,Lucia Mincheva-Nilsson,Marie Cohen,Sandra M. Blois +10 more
TL;DR: The results suggest that gal-1 plays a key role in pregnancy maternal immune regulation by modulating HLA-G expression on trophoblast cells, and could serve as a predictive factor for pregnancy success in early human gestation.
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