Sex- and Age-Specific Differences in COVID-19 Testing, Cases, and Outcomes: A Population-Wide Study in Ontario, Canada.
Nathan M. Stall,Wei Wu,Lauren Lapointe-Shaw,Lauren Lapointe-Shaw,David N. Fisman,Vasily Giannakeas,Vasily Giannakeas,Vasily Giannakeas,Michael P. Hillmer,Michael P. Hillmer,Paula A. Rochon +10 more
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This article is published in Journal of the American Geriatrics Society.The article was published on 2020-08-15 and is currently open access. It has received 34 citations till now. The article focuses on the topics: Population.read more
Citations
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Sex difference in coronavirus disease (COVID-19): a systematic review and meta-analysis.
Biruk Beletew Abate,Ayelign Mengesha Kassie,Mesfin Wudu Kassaw,Teshome Gebremeskel Aragie,Setamlak Adane Masresha +4 more
TL;DR: The prevalence of symptomatic COVID-19 was found to be higher in men than in women, and the high prevalence of smoking and alcohol consumption contributed to thehigh prevalence of CO VID-19 among men.
Journal ArticleDOI
Sex Hormones and Hormone Therapy during COVID-19 Pandemic: Implications for Patients with Cancer.
Carlo Cattrini,Melissa Bersanelli,Maria Maddalena Latocca,Benedetta Conte,Giacomo Vallome,Francesco Boccardo +5 more
TL;DR: The available evidence on sex hormones and hormone therapy in patients infected with SARS-CoV-2 is discussed, and the possible implications for cancer patients, who can receive hormonal therapies during their treatment plans are highlighted.
Journal ArticleDOI
Individual and social determinants of SARS-CoV-2 testing and positivity in Ontario, Canada: a population-wide study.
Maria E. Sundaram,Andrew Calzavara,Sharmistha Mishra,Rafal Kustra,Adrienne K. Chan,Mackenzie A. Hamilton,Mohamed Djebli,Laura Rosella,Tristan Watson,Tristan Watson,Hong Chen,Hong Chen,Hong Chen,Branson Chen,Stefan Baral,Jeffrey C. Kwong,Jeffrey C. Kwong +16 more
TL;DR: This paper explored the potential for collider bias in a large study of disease determinants, and evaluated individual, environmental and social determinants associated with SARS-CoV-2 testing and diagnosis among residents of Ontario, Canada.
Journal ArticleDOI
Risk factors for bacterial infections in patients with moderate to severe COVID-19: A case-control study.
TL;DR: In this article, a case-control study was conducted to determine risk factors for bacterial infection in moderate to critical COVID-19 patients, and significant independent association was found with severe/critical disease at presentation (AOR: 4.42 times; 95% CI: 1.63-11.9).
Posted ContentDOI
Risk factors for bacterial infections in patients with moderate to severe COVID-19: A case control study
TL;DR: Severe or critical COVID-19 at presentation and use of steroids were independently associated with risk of bacterial infections, which have implications for antibiotic stewardship as antibiotics can be reserved for those at higher risk for bacterial superinfections.
References
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Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area.
Safiya Richardson,Safiya Richardson,Jamie S. Hirsch,Jamie S. Hirsch,Mangala Narasimhan,James M. Crawford,Thomas McGinn,Thomas McGinn,Karina W. Davidson,Karina W. Davidson,Douglas P. Barnaby,Douglas P. Barnaby,Lance B Becker,John Chelico,John Chelico,Stuart L. Cohen,Stuart L. Cohen,Jennifer Cookingham,Kevin Coppa,Michael A Diefenbach,Andrew J. Dominello,Joan Duer-Hefele,Louise Falzon,Jordan Gitlin,Negin Hajizadeh,Negin Hajizadeh,Tiffany G. Harvin,David Hirschwerk,Eun Ji Kim,Eun Ji Kim,Zachary Kozel,Lyndonna Marrast,Lyndonna Marrast,Jazmin N. Mogavero,Gabrielle A. Osorio,Michael Qiu,Theodoros P. Zanos +36 more
TL;DR: This case series provides characteristics and early outcomes of sequentially hospitalized patients with confirmed COVID-19 in the New York City area and assesses outcomes during hospitalization, such as invasive mechanical ventilation, kidney replacement therapy, and death.
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COVID-19: the gendered impacts of the outbreak.
TL;DR: Although sex-disaggregated data for COVID-19 show equal numbers of cases between men and women so far, there seem to be sex differences in mortality and vulnerability to the disease, and drug development and clinical evaluation of more potent and specific latency reversal agents alone and in combination are still warranted to determine if this strategy might allow people living with HIV to safely stop ART and achieve a cure.
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Impact of sex and gender on COVID-19 outcomes in Europe.
Catherine Gebhard,Catherine Gebhard,Vera Regitz-Zagrosek,Vera Regitz-Zagrosek,Hannelore Neuhauser,Hannelore Neuhauser,Rosemary Morgan,Sabra L. Klein +7 more
TL;DR: Clinical and epidemiological evidence for gender and sex differences in COVID-19 from Europe and China is summarized and the need to better understand the impact of sex and gender on incidence and case fatality of the disease is emphasized.
Journal ArticleDOI
Biological sex impacts COVID-19 outcomes.
Sabra L. Klein,Santosh Dhakal,Rebecca L. Ursin,Sharvari Deshpande,Kathryn Sandberg,Franck Mauvais-Jarvis +5 more
TL;DR: This work seeks to raise awareness about the male-biased severe outcomes from COVID-19, highlighting the mechanistic differences including in the expression and activity of angiotensin-converting enzyme 2 (ACE2) as well as in antiviral immunity.
Journal ArticleDOI
Sex and Gender Differences in Health: What the COVID-19 Pandemic Can Teach Us.
TL;DR: The authors of this commentary call for sex- and gender-specific and differentiating factors to be urgently included in the research, prevention, and therapeutics implementation response to the coronavirus disease 2019 pandemic.