Journal ArticleDOI
Short-term synaptic plasticity as a temporal filter.
Eric S. Fortune,Gary J. Rose +1 more
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TLDR
This work has suggested that short-term synaptic depression contributes to low-pass temporal filtering, and can account for a well-known paradox - many low- pass neurons respond vigorously to transients and the onsets of high temporal-frequency stimuli.About:
This article is published in Trends in Neurosciences.The article was published on 2001-07-01. It has received 387 citations till now. The article focuses on the topics: Synaptic fatigue & Metaplasticity.read more
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The neural basis of temporal processing
TL;DR: It is suggested that, given the intricate link between temporal and spatial information in most sensory and motor tasks, timing and spatial processing are intrinsic properties of neural function, and specialized timing mechanisms such as delay lines, oscillators, or a spectrum of different time constants are not required.
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Artificial synapse network on inorganic proton conductor for neuromorphic systems
TL;DR: In-plane lateral-coupled oxide-based artificial synapse network coupled by proton neurotransmitters are self-assembled on glass substrates at room-temperature and a strong lateral modulation is observed due to the proton-related electrical-double-layer effect.
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Bursts as a unit of neural information: selective communication via resonance
TL;DR: An alternative, but complementary, hypothesis is discussed: bursts with specific resonant interspike frequencies are more likely to cause a postsynaptic cell to fire than are bursts with higher or lower frequencies, suggesting that bursts of action potentials might provide effective mechanisms for selective communication between neurons.
Bursts as a unit of neural information: selective communication via
TL;DR: In this article, the authors discuss the alternative, but complementary, hypothesis that bursts with specific resonant interspike frequencies are more likely to cause a postsynaptic cell to fire than are bursts with higher or lower frequencies.
Journal ArticleDOI
Surface Mobility of Postsynaptic AMPARs Tunes Synaptic Transmission
Martin Heine,Laurent Groc,Renato Frischknecht,Jean-Claude Béïque,Brahim Lounis,Gavin Rumbaugh,Richard L. Huganir,Laurent Cognet,Daniel Choquet +8 more
TL;DR: It is shown that AMPAR lateral diffusion, observed in both intact hippocampi and cultured neurons, allows fast exchange of desensitized receptors with naïve functional ones within or near the postsynaptic density, which can be explained in part by this fast receptor exchange.
References
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Journal ArticleDOI
Short-Term Synaptic Plasticity
Robert S. Zucker,Wade G. Regehr +1 more
TL;DR: The evidence for this hypothesis, and the origins of the different kinetic phases of synaptic enhancement, as well as the interpretation of statistical changes in transmitter release and roles played by other factors such as alterations in presynaptic Ca(2+) influx or postsynaptic levels of [Ca(2+)]i are discussed.
Journal ArticleDOI
Short-term synaptic plasticity.
TL;DR: The evidence for this hypothesis, the origins of the different kinetic phases of synaptic enhancement, as well as the interpretation of statistical changes in transmitter release and roles played by other factors such as alterations in presynaptic Ca 2+ influx or postsynaptic levels of [Ca 2+]i are discussed.
Journal ArticleDOI
Synaptic depression and cortical gain control
TL;DR: Modeling work based on experimental measurements indicates that short-term depression of intracortical synapses provides a dynamic gain-control mechanism that allows equal percentage rate changes on rapidly and slowly firing afferents to produce equal postsynaptic responses.
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Bursts as a unit of neural information: making unreliable synapses reliable.
TL;DR: Results suggest that the best stimulus for exciting a cell (that is, a neural code) is coincident bursts, which provide more-precise information than action potentials that arrive singly.
Journal ArticleDOI
Redistribution of synaptic efficacy between neocortical pyramidal neurons
Henry Markram,Misha Tsodyks +1 more
TL;DR: In this article, the authors examined synaptic plasticity between individual neocortical layer-5 pyramidal neurons and showed that an increase in the synaptic response, induced by pairing action-potential activity in pre- and postsynaptic neurons, was only observed when synaptic input occurred at low frequencies.
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Synaptic depression and cortical gain control
The neural code between neocortical pyramidal neurons depends on neurotransmitter release probability
Misha Tsodyks,Henry Markram +1 more