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Journal ArticleDOI

Simplified models of screening for chronic disease: estimation procedures from mass screening programmes.

Nicholas E. Day, +1 more
- 01 Mar 1984 - 
- Vol. 40, Iss: 1, pp 1-14
TLDR
The methods are applied to published data from the HIP breast cancer screening project, to which a negative exponential distribution for the sojourn-time distribution fitted better than the other families of distribution considered.
Abstract
The performance of a screening programme depends on a number of parameters, which may need different types of information for their estimation. In this paper, two characteristics of interest, the sojourn-time distribution and the sensitivity, are considered, and estimation procedures, based on data which should be available from a mass screening programme, are proposed. The methods are applied to published data from the HIP breast cancer screening project, to which a negative exponential distribution for the sojourn-time distribution fitted better than the other families of distribution considered.

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Citations
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Journal ArticleDOI

Lead Time and Overdiagnosis in Prostate-Specific Antigen Screening: Importance of Methods and Context

TL;DR: Three independently developed mathematical models of prostate cancer progression and detection were used to estimate lead times and the fraction of overdiagnosed cancers due to PSA screening among US men aged 54-80 years in 1985-2000.
Journal ArticleDOI

IARC Handbooks of Cancer Prevention

TL;DR: The International Agency for Research on Cancer conducts a programme of research concentrating particularly on the epidemiology of cancer and the study of potential carcinogens in the human environment.
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Spectrum of AIDS-associated malignant disorders

TL;DR: Data indicate that AIDS leads to a significantly increased risk of Hodgkin's disease, multiple myeloma, brain cancer, and seminoma, and Immunological failure to control herpes or other viral infections may contribute to these malignant diseases.
Journal ArticleDOI

Overdiagnosis in mammographic screening for breast cancer in Europe: a literature review

TL;DR: The most plausible estimates of overdiagnosis range from 1% to 10%, and substantially higher estimates reported in the literature are due to the lack of adjustment for breast cancer risk and/or lead time.
References
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Book

Cancer Incidence in Five Continents

TL;DR: The aim of this study was to establish a database of histological groups and to provide a level of consistency and quality of data that could be applied in the design of future registries.
Journal ArticleDOI

On the theory of screening for chronic diseases

TL;DR: The purpose of this paper is to discuss statistical considerations associated with the evaluation of such early detection programmes, and to examine problems associated with screening programmes where an individual is examined periodically.
Journal ArticleDOI

Screening for cancer : theory, analysis, and design

TL;DR: A book that makes a significant contribution both to management science and to medical practice is rare, and perhaps unique, but Screening for Cancer: Theory, Analysis, and Design, by David M. Eddy clearly does both.
Journal ArticleDOI

An analysis of the benefits of serial screening for breast cancer based upon a mathematical model of the disease

TL;DR: A model of breast cancer is developed that consists of hypotheses about the age‐specific incidence of the disease, the rate of disease progression, the tendency of the Disease to be detected without benefit of regularly scheduled screening examinations, and prognosis related to the extent of disease at treatment.
Journal ArticleDOI

The theory of periodic screening i: lead time and proportion detected

TL;DR: A stochastic model for a periodic screening program is presented in which the natural history of a chronic disease is assumed to follow a progressive path from a preclinical state to a clinical state.
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