Journal ArticleDOI
Site differences in fat cells of New Zealand obese mice--a transplantation study.
C. J. Meade,Margaret Ashwell +1 more
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TLDR
Fat cells from the gonadal fat pad of New Zealand obese mice are larger than those from the subcutaneous fat pad when fat is transplanted to a third, common site (beneath the kidney capsule), suggesting it is the location of the fat cells rather than of intrinsic differences between the cells that account for their different sizes.Abstract:
Fat cells from the gonadal fat pad of New Zealand obese mice are larger than those from the subcutaneous fat pad. When fat is transplanted to a third, common site (beneath the kidney capsule), this difference in size largely disappears, suggesting it is the location of the fat cells rather than of intrinsic differences between the cells that account for their different sizes.read more
Citations
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Journal ArticleDOI
Variations in glucose metabolism by fat cells from three adipose depots of the rat
Susan K. Fried,Susan K. Fried,Marcelle Lavau,Marcelle Lavau,F. Xavier Pi-Sunyer,F. Xavier Pi-Sunyer +5 more
TL;DR: In this article, the authors isolated from the epididymal (E) and dorsal subcutaneous (S) depots from 150g male Wistar rats were similar in size, but differed markedly in glucose metabolism.
Book ChapterDOI
The comparative anatomy of adipose tissue
TL;DR: This chapter highlights some new perspectives in adipose tissue anatomy that show that early-onset obesity is associated with increased cell numbers, whereas only cell hypertrophy isassociated with adult-onsets obesity.
Journal ArticleDOI
Hypertrophy-Driven Adipocyte Death Overwhelms Recruitment under Prolonged Weight Gain
TL;DR: A qualitatively universal adipose tissue remodeling process in all four fat depots is found, with continuous recruitment of new cells under weight gain and the growth and shrinkage of larger cells is proportional to cell surface area.
Journal ArticleDOI
Structural and histochemical aspects of perirenal adipose tissue in fetal pigs: relationships between stromal-vascular characteristics and fat cell concentration and enzyme activity.
G. J. Hausman,G. B. Thomas +1 more
TL;DR: Assessment of perirenal adipose tissue revealed that the largest fat cell clusters were consistently located near points where large blood vessels entered the loose connective tissue, and reactions for glucose‐6‐phosphate dehydrogenose, lipoprotein lipase and NADH‐TR enzymes were reduced in distal adipocytes compared with proximal adipocytes.
Journal ArticleDOI
Body fat: what is regulated?
TL;DR: The challenge posed by site differences between different depots is focused on, and a variety of experimental approaches that may be helpful are discussed.
References
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Journal ArticleDOI
Cellularity of adipose depots in six strains of genetically obese mice
P. R. Johnson,Jules Hirsch +1 more
TL;DR: A classification for genetic obesity based primarily upon the cellularity characteristics of the adipose depots is proposed.
Journal ArticleDOI
Morphological changes in the adipocyte during fat deposition and mobilization.
TL;DR: It was concluded that the quantity of intracellular fat is an important determinant of the lipid content of a depot; but the volume of an adipocyte is an imperfect measure of its contained lipid.
Journal ArticleDOI
Human fat cell sizing--a quick, simple method.
TL;DR: Method II has several advantages over Method I and it is proposed that it is a suitable method for sizing cells when a quick method with a permanent record is required.
Journal ArticleDOI
Adipose tissue: contributions of nature and nurture to the obesity of an obese mutant mouse (ob/ob).
TL;DR: The internal environment is thus of paramount importance and inherent properties of adipose tissue are of lesser importance in determining obesity in ob/ob mice.