Site-specific regulation of gene expression by n-3 polyunsaturated fatty acids in rat white adipose tissues.
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TLDR
It is concluded that n-3 PUFAs and mainly 22:6n-3 affect gene expression in a site-dependent manner in white adipose tissues via possible antiadipogenic effects.About:
This article is published in Journal of Lipid Research.The article was published on 1997-10-01 and is currently open access. It has received 213 citations till now. The article focuses on the topics: Polyunsaturated fatty acid & Docosahexaenoic acid.read more
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The essentiality of long chain n-3 fatty acids in relation to development and function of the brain and retina.
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Molecular Mechanisms Regulating Hormone-Sensitive Lipase and Lipolysis
TL;DR: The current review summarizes the recent advances with regard to hormone-sensitive lipase structure and molecular mechanisms involved in regulating its activity and lipolysis in general.
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Polyunsaturated fatty acid regulation of genes of lipid metabolism.
Harini Sampath,James M. Ntambi +1 more
TL;DR: Working out the mechanisms by which these interactions and consequent effects occur is proving to be complicated but is invaluable to the understanding of the role that dietary fat can play in disease management and prevention.
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Fatty acid regulation of gene transcription.
TL;DR: The mechanism(s) by which FAs modulate gene transcription still remains largely unresolved and the purpose of the present review is to address this important issue.
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Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce beta-oxidation in white fat.
Pavel Flachs,Olga Horakova,Petr Brauner,Martin Rossmeisl,Petr Pecina,N. Franssen van Hal,Jana Ruzickova,Jana Sponarova,Zdeněk Drahota,C. Vlcek,Jaap Keijer,Josef Houstek,Jan Kopecky +12 more
TL;DR: The anti-adipogenic effect of EPA/DHA may involve a metabolic switch in adipocytes that includes enhancement of β-oxidation and upregulation of mitochondrial biogenesis.
References
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Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
TL;DR: A new method of total RNA isolation by a single extraction with an acid guanidinium thiocyanate-phenol-chloroform mixture is described, providing a pure preparation of undegraded RNA in high yield and can be completed within 4 h.
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A simple method for the isolation and purification of total lipides from animal tissues.
TL;DR: In this paper, the authors described a simplified version of the method and reported the results of a study of its application to different tissues, including the efficiency of the washing procedure in terms of the removal from tissue lipides of some non-lipide substances of special biochemical interest.
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Metabolism of isolated fat cells. i. effects of hormones on glucose metabolism and lipolysis.
The Metabolism of Isolated Fat Cells: I. Effects of Hormones on Glucose Metabolism and Lipolysis
TL;DR: This article marks the beginning of Rodbell's interest in cell receptors and related his discovery that fat cells could be isolated from other cells by treating them with preparations of collagenase, and also found that insulin could stimulate glucose uptake.
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Omega-3 fatty acids in health and disease and in growth and development
TL;DR: Omega 3 fatty acids decrease the number and size of tumors and increase the time elapsed before appearance of tumors, which is essential for the normal functional development of the retina and brain, particularly in premature infants.