Sperm oxidative stress and the effect of an oral vitamin E and selenium supplement on semen quality in infertile men.
L. Keskes-Ammar,N. Feki-Chakroun,Tarek Rebai,Z. Sahnoun,H. Ghozzi,S. Hammami,K. Zghal,H. Fki,J. Damak,A. Bahloul +9 more
TLDR
In contrast to vitamin B supplementation, vitamin E and selenium supplementation produced a significant decrease in MDA concentrations and an improvement of sperm motility, and these results confirm the protective and beneficial effects of Vitamin E and Selenium on semen quality and advocate their use in male infertility treatment.Abstract:
Numerous studies have reported beneficial effects of antioxidant drugs on semen quality, but there is no well-defined therapeutical protocol in male infertility. This study aimed to test the effect...read more
Citations
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Journal ArticleDOI
Oxidative stress and male infertility—a clinical perspective
TL;DR: This review will provide an overview of oxidative biochemistry related to sperm health and identify which men are most at risk of oxidative infertility, and outline methods available for diagnosing oxidative stress and the various treatments available.
Journal ArticleDOI
Selenium in human health and disease.
Susan J. Fairweather-Tait,Yongping Bao,Martin R. Broadley,Rachel Collings,Dianne Ford,John E. Hesketh,Rachel Hurst +6 more
TL;DR: The relationships between selenium intake/status and health, or risk of disease, are complex but require elucidation to inform clinical practice, to refine dietary recommendations, and to develop effective public health policies.
Journal ArticleDOI
Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases
TL;DR: In this paper, the authors provide the best available information on the effect of anti-oxidants on mortality in patients with various diseases, including cancer, heart disease, and stroke.
Journal ArticleDOI
Antioxidant systems and oxidative stress in the testes.
R. John Aitken,Shaun D. Roman +1 more
TL;DR: The testes contain an elaborate array of antioxidant enzymes and free radical scavengers to ensure that the twin spermatogenic and steroidogenic functions of this organ are not impacted by oxidative stress.
Journal ArticleDOI
Antioxidants for male subfertility
Marian Showell,Rebecca Mackenzie-Proctor,Julie Brown,Anusch Yazdani,Marcin T Stankiewicz,Roger Hart +5 more
TL;DR: This Cochrane review aimed to evaluate the effectiveness and safety of oral supplementation with antioxidants for subfertile male partners in couples seeking fertility assistance with a placebo, no treatment or another antioxidant.
References
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Laboratory manual for the examination of human semen and semen-cervical mucus interaction.
TL;DR: This laboratory manual consists of 2 sections which describe methods of examination of human semen and semen-cervical mucus interaction in order to standardize procedures and facilitate evaluation and comparison of research reports.
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World Health Organization Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction, 4th ed.
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Generation of reactive oxygen species, lipid peroxidation, and human sperm function.
TL;DR: Results are consistent with a causative role for lipid peroxidation in the etiology of defective sperm function and also suggest a possible physiological role for the reactive oxygen species generated by human spermatozoa in mediating sperm-zona interaction.
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Role of reactive oxygen species in male infertility.
Rakesh Sharma,Ashok Agarwal +1 more
TL;DR: From the current data it appears that no single adjuvant will be able to enhance the fertilizing capacity of sperm in infertile men, and a combination of the possible strategies that are not toxic at the dosage used would be a feasible approach.
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Vitamin E: Antioxidant Activity, Biokinetics, and Bioavailability
Graham W. Burton,Maret G. Traber +1 more
TL;DR: Pour mesurer l'absorption et le transport de la vitamine E, utilisation d'un isotope stable marque et analyse par chromatographie gazeuse et spectrometrie de masse.