Journal ArticleDOI
Stabilization of serum albumin by anti-inflammatory drugs.
TLDR
Nonsteroidal anti-inflammatory agents inhibited the heat denaturation of serum albumin at drug levels betow 1 mM, as measured by turbidity and viscosity changes.About:
This article is published in Biochemical Pharmacology.The article was published on 1970-03-01. It has received 132 citations till now. The article focuses on the topics: Serum albumin & Blood viscosity.read more
Citations
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Journal ArticleDOI
Perspectives in nonsteroidal anti-inflammatory agents.
TL;DR: Competitive binding and antagonistic interactions between nonsteroidal drugs, particularly salicylate, were observed in vitro and in vivo.
Book ChapterDOI
Inhibition of Prostaglandin Biosynthesis
TL;DR: Some of the events of prostaglandin biosynthesis known to be influenced by chemical agents are indicated, and a logical framework for comparing the relative inhibitory activity of these different agents is suggested.
Journal ArticleDOI
Assessment of multifunctional activity of bioactive peptides derived from fermented milk by specific Lactobacillus plantarum strains
J.E. Aguilar-Toalá,Lourdes Santiago-López,C. Peres,Cidália Peres,Hugo S. Garcia,Belinda Vallejo-Cordoba,Aarón F. González-Córdova,Adrián Hernández-Mendoza +7 more
TL;DR: Assessment of the anti-inflammatory, antihemolytic, antioxidant, antimutagenic, and antimicrobial activities of crude extracts and peptide fractions obtained from fermented milks with specific Lactobacillus plantarum strains provides valuable evidence of multifunctional role of peptides derived of fermented milk by the action of specific L. plantarUM strains.
Journal Article
The in vitro anti-denaturation effects induced by natural products and non-steroidal compounds in heat treated (immunogenic) bovine serum albumin is proposed as a screening assay for the detection of anti-inflammatory compounds, without the use of animals, in the early stages of the drug discovery process.
Lawrence A. D. Williams,A O'Connar,L Latore,O Dennis,S Ringer,J. A. Whittaker,Jürgen Conrad,Bernhard Vogler,Harald Rösner,Wolfgang Kraus +9 more
TL;DR: In this paper, the authors proposed using the in vitro anti-denaturation (stabilization) effects of heat treated (immunogenic) bovine serum albumin (BSA) as an assay.
Journal ArticleDOI
Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6–diphenyl–1,2,4–triazin–3(2H)–one derivatives bearing 5–substituted 1,3,4–oxadiazole as potential anti–inflammatory and analgesic agents
Anupam G. Banerjee,Nirupam Das,Sushant A. Shengule,Radhey Shyam Srivastava,Sushant K. Shrivastava +4 more
TL;DR: A series of triazin-3(2H)-one derivatives bearing 1,3,4-oxadiazole (4a-4o) were synthesized, characterized and evaluated for anti-inflammatory and analgesic activities and verified the consensual interaction of these compounds with the enzyme.
References
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Journal ArticleDOI
Interaction of anti-inflammatory drugs with serum proteins, especially with some biologically active proteins
Y Mizushima,M Kobayashi +1 more
TL;DR: Phenylbutazone and sodium salicylate do not inhibit the biological activity of three biologically active and labile serum proteins, namely, necrotizing factor, heterogenous serum and complement, however, they do influence the effect of heat on these proteins.
Journal ArticleDOI
Preparation of human serum albumin free of long-chain fatty acids.
Journal ArticleDOI
Isomerization reactions of charcoal-defatted bovine plasma albumin. The N-F transition and acid expansion
Masaru Sogami,Joseph F. Foster +1 more
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Interaction of anti-inflammatory drugs with serum proteins, especially with some biologically active proteins
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