Journal ArticleDOI
Steric Course and Specificity of α-Chymotrypsin-catalyzed Reactions. I
George E. Hein,Carl Niemann +1 more
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This article is published in Journal of the American Chemical Society.The article was published on 1962-12-01. It has received 94 citations till now. The article focuses on the topics: Chymotrypsin & Steric effects.read more
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Metals and DNA: molecular left-handed complements
TL;DR: These site-specific chiral metal complexes provide exciting new tools for probing the local variations in DNA structure and its role in the regulation of gene expression.
Journal ArticleDOI
Asymmetric syntheses with chiral oxazaborolidines
Sabine Wallbaum,Jürgen Martens +1 more
Journal ArticleDOI
The enantiomeric ratio: origin, determination and prediction
TL;DR: The outstanding characteristics of the enantiomeric ratio as a quantitative measure of the effects of physical and chemical conditions on the intrinsic enantioselectivity of enzymes are presented in terms of the difference in Gibbs energies of the diastereomeric enzyme-substrate transition states.
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A simple method to determine the enantiomeric ratio in enantioselective biocatalysis
TL;DR: Values for E and the thermodynamic equilibrium constant, KEQ, were obtained for a (DL)-dehalogenase-catalyzed dehalogenation, a hydrolysis reaction by porcine pancreatic lipase, and for Cylindracea lipase-Catalyzed esterification and transesterification.
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Chymotrypsin: molecular and catalytic properties.
TL;DR: A review on the peptide hydrolase chymotrypsin gives some characteristics concerning the structure, specificity, mechanism of activation from its precursor and catalytic activity, and diagnostic role of this serine proteinase.