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Journal ArticleDOI

Stress distributions and material properties determined in articular cartilage from MRI-based finite strains

Kent D. Butz, +3 more
- 13 Oct 2011 - 
- Vol. 44, Iss: 15, pp 2667-2672
TLDR
The results demonstrate the feasibility of a new and computationally efficient technique incorporating MRI-based deformation with mathematical modeling to non-invasively evaluate the mechanical behavior of biological tissues and materials.
About
This article is published in Journal of Biomechanics.The article was published on 2011-10-13. It has received 44 citations till now. The article focuses on the topics: Stress (mechanics) & Finite element method.

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Citations
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Journal ArticleDOI

Diurnal Variations in Articular Cartilage Thickness and Strain in the Human Knee

TL;DR: The findings of this study show that human knee cartilage undergoes diurnal changes in strain that vary with site in the joint, and provides a baseline for future studies investigating the effects of altered biomechanics on diurnal cartilage strains and cartilage physiology.
Journal ArticleDOI

In vivo articular cartilage deformation: noninvasive quantification of intratissue strain during joint contact in the human knee.

TL;DR: The MRI-based approach may accelerate the development of regenerative therapies for diseased or damaged cartilage, which is currently limited by the lack of reliable in vivo methods for noninvasive assessment of functional changes following treatment.
Journal ArticleDOI

Mechanical properties of normal and osteoarthritic human articular cartilage.

TL;DR: The results identify the limits by which isotropic hyperelastic material models may be used to describe cartilage contact variables, indicating that the mechanical properties of cartilage for large strains change with tissue damage.
Journal ArticleDOI

Multiscale Mechanics of Articular Cartilage: Potentials and Challenges of Coupling Musculoskeletal, Joint, and Microscale Computational Models

TL;DR: This review outlines recent modeling and simulation approaches to understand cartilage function from a mechanical systems perspective, and illustrates pathways to associate mechanics with biological function.
Journal ArticleDOI

In Vivo Measurement of Localized Tibiofemoral Cartilage Strains in Response to Dynamic Activity

TL;DR: Local regions of both the femur and tibia experienced significant cartilage strains as a result of dynamic activity, and an understanding of changes in cartilage strain distributions may help to elucidate the biomechanical factors contributing to cartilage degeneration after joint injury.
References
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National Arthritis Data Work-group. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II

TL;DR: In this paper, the best available estimates of the US prevalence of and number of individuals affected by osteoarthritis, polymyalgia rheumatica and giant cell arteritis, gout, fibromyalgia, and carpal tunnel syndrome, as well as the symptoms of neck and back pain are provided.
Journal ArticleDOI

Cartilage and diarthrodial joints as paradigms for hierarchical materials and structures

TL;DR: This review presents a summary of the hierarchical features for articular cartilage and diarthrodial joints and tables of known material properties for cartilage to summarize how the multi-scale interactions in articular Cartilage provide for its unique material properties and tribological characteristics.
Journal ArticleDOI

Effects of idealized joint geometry on finite element predictions of cartilage contact stresses in the hip.

TL;DR: The results demonstrate that simplifications to the geometry of the bone-cartilage interface, cartilage surface and bone material properties can have a dramatic effect on the predicted magnitude and distribution of cartilage contact pressures in the hip joint.
Journal ArticleDOI

A subject specific multibody model of the knee with menisci.

TL;DR: A subject specific computational model of the knee with menisci that can be incorporated into neuromusculoskeletal models within a multibody framework is developed and placed within a dynamic knee simulator model.
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