Journal ArticleDOI
Structure of the tubular variants of the head of bacteriophage T4 (polyheads). II. Structural transition from a hexamer to a 6+1 morphological unit.
TLDR
It is suggested that the in vitro transformation from the 6- to the 6 + 1-type of morphological unit is correlated with the cleavage of protein components which accompany the normal assembly (Laemmli, 1970), and may mimic an in vivo structural transformation.About:
This article is published in Journal of Molecular Biology.The article was published on 1972-04-14. It has received 47 citations till now. The article focuses on the topics: Random hexamer.read more
Citations
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Journal ArticleDOI
Three-dimensional structure determination by electron microscopy of two-dimensional crystals
Journal ArticleDOI
Microtubule surface lattice and subunit structure and observations on reassembly.
TL;DR: The 40 x 50 Å morphological subunit, which has previously been seen only as a globular particle and identified as the 55,000-dalton tubulin monomer, is seen in this higher resolution reconstructed image to be elongated, and split symmetrically by a longitudinal cleft into two lobes.
Journal ArticleDOI
A study of the structure of the T-layer of Bacillus brevis.
Journal ArticleDOI
Assembly core of bacteriophage T4: an intermediate in head formation.
TL;DR: An unstable assembly core initiates phage T4 head formation and T4 core proteins—P22 and internal proteins—nucleate capsid assembly but have no structural role in the completed capsid.
References
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Journal ArticleDOI
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products.
Journal Article
Cleavage of structural proteins during the assemble of the head of bacterio-phage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products as mentioned in this paper.
Journal ArticleDOI
Form-determining function of the genes required for the assembly of the head of bacteriophage T4.
Ulrich K. Laemmli,Ulrich K. Laemmli,E Mölbert,E Mölbert,M Showe,M Showe,E. Kellenberger,E. Kellenberger +7 more
TL;DR: The physiological manifestation of conditional lethal mutations in the genes involved in the formation of the T4 head have been re-examined in this paper, where the minimum number of head genes whose active product is needed to form the various head-related structures has been determined by examining infection by a series of double mutants.
Journal ArticleDOI
Studies on the morphopoiesis of the head of phage T-even III. The cores of head-related structures
E. Kellenberger,E. Kellenberger,F.A. Eiserling,F.A. Eiserling,E. Boy de la Tour,E. Boy de la Tour +5 more
TL;DR: The present information from morphological, genetic, and biochemical experiments strongly suggests that the observed cores of bacteriophage T4 contain an internal component defined as a core and have a morphopoietic role.
Journal ArticleDOI
Structure of the tubular variants of the head of bacteriophage T4 (polyheads). I. Arrangement of subunits in some classes of polyheads.
David J. DeRosier,Aaron Klug +1 more
TL;DR: Electron micrographs of tubular variants of the head of bacteriophage T4 arising from a mutation in gene 20 have been analysed by means of optical diffraction and filtering, and four main classes of tube have been observed.
Related Papers (5)
Optical filtering of electron micrographs: reconstruction of one-sided images.
Aaron Klug,D. J. De Rosier +1 more
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
An optical method for the analysis of periodicities in electron micrographs, and some observations on the mechanism of negative staining.
A. Klug,J.E. Berger +1 more