Journal ArticleDOI
Studies on the immunomodulatory effects of Ashwagandha.
TLDR
Treatment with Ashwagandha was accompanied by significant increases in hemolytic antibody responses towards human erythrocytes, which prevented myelosuppression in mice treated with all three immunosuppressive drugs tested.About:
This article is published in Journal of Ethnopharmacology.The article was published on 1996-02-01. It has received 360 citations till now. The article focuses on the topics: Withania somnifera & White blood cell.read more
Citations
More filters
Journal ArticleDOI
Estimation of antioxidant potential of individual components present in complex mixture of Withania somnifera (Ashwagandha) root fraction by thin-layer chromatography-2,2-diphenyl-1-picrylhdrazyl method
TL;DR: In this paper, a thin-layer chromatography-2,2-diphenyl-1-picrylhdrazyl (TLC-DPPH) method has been developed for the quantification of withanolides and simultaneous estimation of antioxidant potential of each constituent present in a complex mixture.
Journal ArticleDOI
Immunomodulatory Effect of Withania somnifera (Ashwagandha) Extract—A Randomized, Double-Blind, Placebo Controlled Trial with an Open Label Extension on Healthy Participants
Ajit Tharakan,Himanshu H. Shukla,Irin Rosanna Benny,Matthan Tharakan,Lekha George,Santhosh Koshy +5 more
TL;DR: The immunomodulatory effect of Withania somnifera (WS) extract was tested in healthy adults in a randomized placebo-controlled double-blinded study as discussed by the authors, where subjects were allocated either 60 mg WS extract or placebo.
BookDOI
Biochemical roles of eukaryotic cell surface macromolecules
TL;DR: Human-Specific Evolutionary Changes in the Biology of Siglecs structural changes of GPI Anchor after its Attachment to Proteins and novel Insights in Membrane Biology Utilizing Fluorescence Recovery after Photobleaching are outlined.
Journal ArticleDOI
RNAi of Sterol Methyl Transferase1 Reveals its Direct Role in Diverting Intermediates Towards Withanolide/Phytosterol Biosynthesis in Withania somnifera
Shaifali Pal,Shubhra Rastogi,Dinesh A. Nagegowda,Madan M. Gupta,Ajit Kumar Shasany,Ajit Kumar Shasany,Chandan S. Chanotiya +6 more
TL;DR: The results established that SMT1 plays a crucial role in W. somnifera withanolide biosynthesis predominantly through the campesterol and stigmasterol routes.
Journal ArticleDOI
Pseudomonas aeruginosa WS-1 for biological control of leaf blight disease of Withania somnifera
TL;DR: Pseudomonas aeruginosa strain WS-1 isolated from the rhizosphere, showed both in vitro and in vivo antagonistic activity against the pathogen.
References
More filters
Book
The pharmacological basis of therapeutics
TL;DR: In this article, 42 authors share the herculean task of reviewing the flood of recent literature on pharmacology and rational use of drugs, under single or dual authorship they contribute the 76 chapters in the 18 sections.
Book
Thin-layer chromatography : a laboratory handbook
TL;DR: Thin-Layer Chromatography edited by E. Stahl (+) is the standard laboratory reference book for applications of this analytical method in chemical, pharmaceutical and clinical analysis.
Journal ArticleDOI
A comparative pharmacological investigation of Ashwagandha and Ginseng.
TL;DR: The aqueous suspensions of roots of an Indian drug Ashwagandha and the Korean drug Ginseng were tested comparatively for 2 pharmacological activities, namely the anti-stress activity by the 'mice swimming endurance test' and anabolic activity by noting gain in body weights and levator ani muscle in rats.