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Substituent Effects in the Intramolecular Diels−Alder Reaction of 6-Furylhexenoates
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In this paper, the series of furyl enone esters, 4a−c, were synthesized from furan or furfural by straightforward routes, and their thermal intramolecular Diels−Alder reactions to give the tricyclic ketones 5a−C were...Abstract:
The series of furyl enone esters, 4a−c, were synthesized from furan or furfural by straightforward routes. Their thermal intramolecular Diels−Alder reactions to give the tricyclic ketones 5a−c were...read more
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Gem-Disubstituent Effect: Theoretical Basis and Synthetic Applications
Michael E. Jung,Grazia Piizzi +1 more
TL;DR: A comparison study of the effects of gem-Dialkyl Substitution in Drug Design on the Formation and Stability of Inorganic and Organometallic Complexes and their implications for synthetic chemistry and drug design.
Journal ArticleDOI
Carbon−Carbon Bond Formations Involving Organochromium(III) Reagents
Journal ArticleDOI
The Type 2 Intramolecular Diels–Alder Reaction: Synthesis and Chemistry of Bridgehead Alkenes
TL;DR: The type 2 intramolecular Diels-Alder reaction and the resulting anti-Bredt alkenes have found application in organic synthesis and are verified in recent applications of the type 2 IMDA reaction as a key step in the total synthesis of complex natural products.
Journal ArticleDOI
Methodology and applications of the hexadehydro-Diels–Alder (HDDA) reaction
TL;DR: The hexadehydro-Diels-Alder (HDDA) reaction between an alkyne and a 1,3-diyne has recently become a rapidly growing area in the field of aryne chemistry as mentioned in this paper.
Journal ArticleDOI
Cycloaddition chemistry of 2-vinyl-substituted indoles and related heteroaromatic systems.
TL;DR: The intramolecular Diels-Alder cycloaddition reaction (IMDAF) of several N-phenylsulfonylindolyl-substituted furanyl carbamates containing a tethered pi-bond on the indole ring was examined as an approach to the iboga alkaloid catharanthine.
References
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Journal ArticleDOI
CXIX.—The formation and stability of spiro-compounds. Part I. spiro-Compounds from cyclohexane
Journal ArticleDOI
XLVI. On the determination of the velocity constant of a unimolecular reaction
TL;DR: In this article, the determination of the velocity constant of a unimolecular reaction is discussed. But the authors focus only on the case where the reaction can be seen as a single particle.
Journal ArticleDOI
Catalytic effect of nickel(II) chloride and palladium(II) acetate on chromium(II)-mediated coupling reaction of iodo olefins with aldehydes
Journal ArticleDOI
Selective grignard-type carbonyl addition of alkenyl halides mediated by chromium(II) chloride
TL;DR: Alkenyl iodide (or bromide) is readily reduced with CrCl2 is N,N-dimethylformamide at 25°C to gice the corresponding organochromium species which adds selectively to an aldehyde moiety without affecting the coexisting ketone or cyano group of the substrate.
Journal ArticleDOI
Gem-dialkyl effect in the intramolecular diels-alder reaction of 2-furfuryl methyl fumarates : the reactive rotamer effect, enthalpic basis for acceleration, and evidence for a polar transition state
Michael E. Jung,Jacquelyn Gervay +1 more
TL;DR: In this paper, the authors investigated the rates of cyclization of a series of substituted 2-furfuryl methyl fumarates and determined which of the two explanations for the gem-dialkyl effect is more important.
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Gem-dialkyl effect in the intramolecular diels-alder reaction of 2-furfuryl methyl fumarates : the reactive rotamer effect, enthalpic basis for acceleration, and evidence for a polar transition state
Michael E. Jung,Jacquelyn Gervay +1 more