Journal ArticleDOI
Swallowing problems in Parkinson disease: frequency and clinical correlates
TLDR
Self-report of ’no difficulty’ is not a reliable indicator of swallowing ability and studies employing more-objective assessment of aspiration risk to compare with water swallow test performance are advocated.Abstract:
Background: Changes to the efficiency and integrity of swallowing mechanisms are inevitable in Parkinson disease (PD); however, it remains unclear how many people with PD are at risk of dysphagia. The aim of this study was to establish the frequency of impaired swallowing in people with PD and the relationship between swallowing performance and indicators of disease progression. Methods: A community-based and hospital-based cohort of 137 individuals with PD were asked to drink 150 ml of water as quickly as possible while in an ‘off drug’ state. Results: Thirty-one (23%) patients could not completely drink the full 150 ml. Swallowing rate (ml/sec) fell to more than 1SD below published norms for 115 (84%) patients and to more than 2SD below for 44 (32%) individuals. There were moderate correlations between rate of swallowing and disease severity, depression and cognition, but not between swallowing speed and disease duration. There was poor correlation between subjective reports of dysphagia and performance on the water swallow test. Conclusions: Swallowing problems are frequent in PD. Self-report of ’no difficulty’ is not a reliable indicator of swallowing ability. Studies employing more-objective assessment of aspiration risk to compare with water swallow test performance are advocated.read more
Citations
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European Society for Swallowing Disorders - European Union Geriatric Medicine Society white paper: oropharyngeal dysphagia as a geriatric syndrome.
Laura W. J. Baijens,Pere Clavé,Patrick Cras,Olle Ekberg,Alexandre Forster,Gerald F. Kolb,Jean Claude Leners,Stefano Masiero,Jesús Mateos-Nozal,Omar Ortega,David G. Smithard,Renée Speyer,Margaret Walshe +12 more
TL;DR: Oropharyngeal dysphagia should be given more importance and attention and thus be included in all standard screening protocols, treated, and regularly monitored to prevent its main complications.
Journal ArticleDOI
Prevalence of oropharyngeal dysphagia in Parkinson’s disease : A meta-analysis
TL;DR: In this article, the authors performed a meta-analysis to estimate the prevalence of oropharyngeal dysphagia in Parkinson's patients, using subjective outcomes and objective measures.
Journal ArticleDOI
Dysphagia in Parkinson's Disease
Inga Suttrup,Tobias Warnecke +1 more
TL;DR: An overview on current stages of epidemiology, pathophysiology, diagnosis, and treatment of PD-associated dysphagia is given, which might be helpful for neurologists, speech-language therapists, and other clinicians in their daily work with PD patients and associated swallowing difficulties.
Journal ArticleDOI
ESPEN guideline clinical nutrition in neurology
Rosa Burgos,Irene Bretón,Emanuele Cereda,Jean Claude Desport,Rainer Dziewas,Laurence Genton,Filomena Gomes,Pierre Jésus,Andreas H. Leischker,Maurizio Muscaritoli,K.A. Poulia,Jean-Charles Preiser,Marjolein A. van der Marck,Rainer Wirth,Pierre Singer,Stephan C. Bischoff +15 more
TL;DR: An evidence- and consensus-based guideline addresses clinical questions on best medical nutrition therapy in patients with neurological diseases and offers 88 recommendations for use in clinical practice for amyotrophic lateral sclerosis, Parkinson's disease, stroke and multiple sclerosis.
Journal ArticleDOI
The influence of age and gender on motor and non-motor features of early Parkinson's disease: Initial findings from the Oxford Parkinson Disease Center (OPDC) discovery cohort
Konrad Szewczyk-Krolikowski,Paul R. Tomlinson,Kannan Nithi,Richard Wade-Martins,Kevin Talbot,Yoav Ben-Shlomo,Michele T.M. Hu,Michele T.M. Hu +7 more
TL;DR: Age in PD is a strong factor contributing to disease severity even after controlling for the effect of disease duration, and gender-related motor phenotype can be defined by a vertical split into more symmetrical upper-body disease in men and disease dominated by postural symptoms in women.
References
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Journal ArticleDOI
Parkinsonism: Onset, progression, and mortality
Margaret M. Hoehn,Melvin D. Yahr +1 more
TL;DR: Controversy over the effectiveness of therapeutic measures for parkinsonism is due partially to this wide variability and to the paucity of clinical information about the natural history of the syndrome.
Journal ArticleDOI
Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases.
TL;DR: The pathological findings in 100 patients diagnosed prospectively by a group of consultant neurologists as having idiopathic Parkinson's disease are reported, and these observations call into question current concepts of Parkinson's Disease as a single distinct morbid entity.
Journal ArticleDOI
Variable expression of Parkinson's disease A base‐line analysis of the DAT ATOP cohort
Joseph Jankovic,Michael P. McDermott,Jonathan T Carter,Susan A. Gauthier,Christopher G. Goetz,Lawrence I. Golbe,S. Huber,William C. Koller,C. W. Olanow,Ira Shoulson,Matthew B. Stern,Caroline M. Tanner,William J. Weiner +12 more
TL;DR: The DATATOP database as discussed by the authors includes clinical information on 800 patients with early untreated Parkinson's disease (PD) and is well suited to explore clinical heterogeneity in PD patients, including Bradykinesia, and postural instability and gait difficulty (PIGD).
Journal ArticleDOI
Hard to swallow: dysphagia in Parkinson’s disease
TL;DR: If and how changes in swallowing impact on the lives of people with Parkinson's disease is established and the psychosocial consequences of the physical changes concerned people most.
Journal ArticleDOI
Test characteristics of the 15-item geriatric depression scale and Hamilton depression rating scale in Parkinson disease.
TL;DR: The GDS-15 performs well as a screening instrument and in distinguishing depressed from nondepressed patients in PD and its test characteristics are comparable to the HDRS.